Results 91 to 100 of about 1,141 (209)

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

From "warning" to "guidance": design of a closure control zone for eight-lane freeways and evaluation of its regulating effects on driving behavior. [PDF]

Front Public Health
Zhao X, Bei R, Zhang J, Ling Y, Yang X.
europepmc   +1 more source

Bypassing Pre‐Photoactivation in High‐Barrier Polyamide for Robust and Scalable Organic Persistent Luminescence

Advanced Science, EarlyView.
A universal paradigm resolves the trade‐off between ambient stability and barrier properties in organic persistent luminescent (OPL) polymers. By interlocking chromophores within a high‐barrier MXD6 matrix, we achieved no Pre‐photoactivation OPLs with exceptional long‐term stability in water.
Yunlong Yang, Sha Liu, Shilin Bo, Longming Jin, Baijun Tang, Zhiying Guo, Chengtao Gao, Xionggang Wang, Yuejun Liu, Qiang Zheng, Zi Liang Wu   +10 more
wiley   +1 more source

A Review of Research on Throwing Biomechanics, Upper Extremity Injuries, and Treatment of Throwing Injuries in Professional Baseball and Football. [PDF]

Orthop J Sports Med
Tewari K, Sun B, Sridharan M, Olson T, Streeter S, Walker P, Hame S, Petrigliano F.   +7 more
europepmc   +1 more source

Optimized protocol for quantification of extracellular nicotinamide adenine dinucleotide: evaluating clinical parameters and pre-analytical factors for translational research. [PDF]

Front Med (Lausanne), 2023
Saqr AA, Kamali C, Brunnbauer P, Haep N, Koch P, Hillebrandt KH, Keshi E, Moosburner S, Mohr R, Raschzok N, Pratschke J, Krenzien F.   +11 more
europepmc   +1 more source

Stark decelerator for Rydberg atoms and molecules

, 2009
This thesis deals with the achievement of a supersonic beam of sodium atoms. Theses atoms are excited into a Rydberg state. We use the interaction between the huge dipole momenta of these states and time dependant inhomogeneous electric field. The supersonic beam of sodium atoms is produced by laser ablation, characterized by laser induced fluorescence
openaire   +1 more source

Taming Flexibility: Synergistic Pore and Polarity Engineering in a MOF for High‐Efficiency Xe/Kr Separation

Advanced Science, EarlyView.
Through a mixed‐ligand strategy that precisely regulates pore size and framework polarity, the Xe adsorption behavior is transformed from flexible to near‐rigid. ZIF‐7‐Cl(20) achieves sensitive recognition, efficient capture, and high selectivity for Xe, enabling high‐efficiency separation from Xe/Kr mixtures.
Tao Zhao, Xue Wang, Youjin Gong, Siqi Dong, Shunshun Xiong, Hui Xu, Aziz Bakhtiyarovich Ibragimov, Thamraa Alshahrani, He Zheng, Lin Li, Junkuo Gao   +10 more
wiley   +1 more source

Deceleration and rebound of hemagglutinin divergence in influenza B/Victoria across COVID-19 NPI phases (2016-2024). [PDF]

Front Microbiol
Zhang Y, Fu B, Yu C, Liu S, Wang Y, Wang Z, Wang K.   +6 more
europepmc   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Distributions of plantar loads are altered when walking in anxiety-inducing virtual settings but not under cognitive demand. [PDF]

PLoS One
Poretti K, Stark NEP, Wade FE, Fino PC, Raffegeau TE.   +4 more
europepmc   +1 more source