Results 71 to 80 of about 1,141 (209)

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Rotational-state purity of Stark-decelerated molecular beams

, 2011
Cold, velocity-controlled molecular beams consisting of a single quantum state promise to be a powerful tool for exploring molecular scattering interactions. In recent years, Stark deceleration has emerged as one of the main methods for producing velocity-controlled molecular beams.
Fitch, N. J., Esteves, D. A., Fabrikant, M. I., Briles, T. C., Shyur, Y., Parazzoli, L. P., Lewandowski, H. J.   +6 more
openaire   +2 more sources

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal

Advanced Science, EarlyView.
We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao, Yi Hou, Jie Zhang, Bo Wang, Minghui Guo, Hua Qu, Wei Rao, Jing Liu   +7 more
wiley   +1 more source

Experiments with Stark-decelerated and trapped molecules

, 2009
139 p.
openaire   +2 more sources

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source

Tailoring Multifunctional Carbon Dots via Precursor Stoichiometry: Switching Between Solid‐State Fluorescence and Broadband Absorption Through Aggregation Control

Advanced Science, EarlyView.
Precursor stoichiometry programs the surface chemistry of carbon dots, directing their self‐assembly into distinct aggregation modes. Aldehyde‐enriched surfaces form ordered, hydrogen‐bonded assemblies that enable bright red solid‐state fluorescence, whereas amine‐rich surfaces promote compact π–π stacked aggregates with broadband visible‐light ...
Gaixia Yang, Hao Sun, Defa Hou, Fulin Yang, Yuan Zou, Bei Zhou, Lanxiang Liu, Xu Lin, Guanben Du   +8 more
wiley   +1 more source

An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity

Advanced Science, EarlyView.
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao, Xuemei Sun, He Li, Bangming Wang, Mengting Pan, Zhen Ma, Rong‐Mei Kong, Weiheng Kong, Yan Zhao, Fengli Qu   +9 more
wiley   +1 more source

Hydrogel Stack‐Tailored Logics and High‐Fidelity Multimodal Sensors Promoted by Precisely Evaluated Ionic Migration

Advanced Science, EarlyView.
Inspired by biological ion transport, this work introduces self‐powered multifunctional sensors utilizing tailored hydrogel stacks. Optimizing ionic migration with MXenes and carbon nanotubes achieves high‐performance energy harvesting and unique logic circuit functionality.
Haoran Chen, Hongjian Zhang, Zhonghui Shen, Taeuk Eom, Hyunseung Kim, Delong He, Jinbo Bai, Geon‐Tae Hwang, Yong Zhang, Chang Kyu Jeong   +9 more
wiley   +1 more source