Results 161 to 170 of about 43,527 (197)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Risk factors for depression in systemic lupus erythematosus: a systematic review and meta-analysis. [PDF]

Front Med (Lausanne)
Zhu L, Chen J, Sha Y, Zhuang H, Ye C.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Association between anaemia and osteoporosis: a systematic review and meta-analysis. [PDF]

Ann Med
Tear AA, Tesno FA, Shofiadeita H, Bunga GM, Taqiya HN, Sanditha NA, Fayyaza AH, Tambunan SKT, Wangsa GK, Fatimah QR, Istiqomah I, Wibawanty W, Lubis L.   +12 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Outcomes of Fixation of Lateral-End Clavicle Fractures Using Locking Clavicular Plate With Acromioclavicular TightRope Augmentation: A Meta-Analysis. [PDF]

Cureus
Memon K, Awan M, Abro AA, Ahmad S, Shehata Abdelmesih SR.   +4 more
europepmc   +1 more source

Impact of Hyaluronic Acid Around Dental Implants: A Systematic Review. [PDF]

J Int Soc Prev Community Dent
Ananya S, Palwankar P, Pandey R.
europepmc   +1 more source