Results 91 to 100 of about 32,290 (218)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

B-type host stars revealed by exoplanets around massive secondary-clump giant stars. [PDF]

Nat Commun
Lin WX, Qian SB, Sun QB, Zhu LY, Liao WP, Li T, Li FX, Liu L, Shi XD, Li L, Zhao E, Zhang H, Li P, Li J, Lian M.   +14 more
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Whole-Brain 4D MRA With Improved Vessel Delineation Using Undersampled Multiple Overlapping Thin-Slab Radial Acquisition. [PDF]

NMR Biomed
Zhao T, Chung SH, He Y, Huang Z, Tang J, Ansari SA, Yan L.   +6 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Discovery of a star sensitive to the spin of Sagittarius A. [PDF]

Nature
Abd El Dayem K, Abuter R, Aimar N, Amaro-Seoane P, Berdeu A, Berger JP, Bourdarot G, Brandner W, Burkert A, Calderón D, Correia C, Cuadra J, Davies R, Defrère D, Delit L, Drescher A, Eisenhauer F, Esteras Otal L, Fabricius M, Feuchtgruber H, Flesch S, Förster Schreiber NM, Foschi A, Fournier Q, Garcia P, Garcia Lopez R, Generozov A, Genzel R, Gillessen S, Gonté F, Haubois X, Hönig SF, Houllé M, Joharle S, Kaufer A, Kammerer J, Kervella P, Kolb J, Kreidberg L, Labadie L, Lacour S, Lai O, Laugier R, Le Bouquin JB, Leftley J, Li R, Lopez B, Lutz D, Mang F, Mérand A, Millour F, Montargès M, Morujão N, Nowacki H, Nowak M, Oberti S, Osorno J, Ott T, Paumard T, Paladini C, Pappert S, Perets HB, Perraut K, Perrin G, Petrov R, Petrucci PO, Piran T, Pourré N, Rabien S, Ribeiro DC, Robbe-Dubois S, Sadun Bordoni M, Sanchez-Bermudez J, Santos D, Sari R, Sauter J, Scheithauer S, Scigliuto J, Shangguan J, Shimizu TT, Soulez F, Stadler J, Straubmeier C, Sturm E, Subroweit M, Sykes C, Tacconi LJ, Thévenet P, Urso I, Vincent F, Woillez J, Zins G, GRAVITY+ Collaboration.   +92 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Performance Evaluation, Optical Optimization and Earth-Based Validation of Star Sensors for Ground Detection in Martian Dust Environments. [PDF]

Sensors (Basel)
Gao Y, He MJ, Li Y, Wang HY, Li SL, Qi H.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Comparison of liver T1 estimates generated by breath-hold 3D FSPGR and free-breathing 3D radial stack-of-stars FSPGR variable flip angle T1 mapping sequences. [PDF]

Eur J Radiol Open
Xu H, Hou Z, Zhang M, Guo R, Zhang J, Fu G, Wen Q, Li Z, Tao F, Yang S.   +9 more
europepmc   +1 more source