Results 131 to 140 of about 51,001 (265)

Modelling dynamos in rapidly rotating late-type stars

open access: yes
There is growing observational evidence that magnetic activity in rapidly rotating late-type stars is very different from that found in the Sun. In particular, polar spots and other high-latitude features are often observed on rapid rotators.
Bushby PJ
core  

Infrared Observations of Late Type Stars

open access: yes, 1977
Substantive mass loss resulting in appreciable circumstellar dust envelopes is common in late-type stars. The evolutionary history and physical state of a cool star determine the chemistry within the outer stellar atmosphere mirrored by the molecular and
Merrill, K. M.
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

18th Cambridge Workshop on Cool Stars, Stellar Systems, and the Sun: Cool Stars 18

open access: yes, 2014
The cyclic magnetic activity of the modern-day Sun is generally considered to be powered by a self-regenerating interface-layer dynamo. However, Zeeman Doppler Imaging of the spots and magnetic fields of active young solar-type stars suggests that a ...
Waite, I. A.   +2 more
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

The abundances of carbon and nitrogen in the atmospheres of classical Be stars. [PDF]

open access: yesAstrophys Space Sci
Peters GJ   +4 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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