Results 71 to 80 of about 51,078 (265)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hot Stars with Cool Companions [PDF]

open access: yes, 2014
We present intermediate results of a spectroscopic survey for late K-M companions orbiting nearby A and B type stars. Such companions may have formed in the massive disk of the young primary star, and so may be scaled-up versions of brown dwarfs formed ...
Gullikson, Kevin (5274238)   +5 more
core   +1 more source

The Chemical Composition of Late Type Stars [PDF]

open access: yesSymposium - International Astronomical Union, 1974
A discussion is given of the chemical composition of the atmospheres of various types of late type peculiar stars and their compositions are compared with those of normal K and M stars. The groups considered include CN, CH, Ba, S, C, R CrB and HdC stars.
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Photometric parallaxes and subdwarf identification for M-type stars [PDF]

open access: yes, 2012
Photometric data on the Kron-Cousins photometric system have been obtained for 118 new late K to middle M-type stars with known distances. These data have been used to obtain absolute red magnitudes, to construct a color-magnitude diagram, and to compute
Thompson, Dayna L.
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Investigating the A-Type Stars Using Kepler Data [PDF]

open access: yes, 2013
Rotation is a key physical process operating in the A stars. We present a method by which rotation periods might be measured with Fourier transforms of Kepler data, potentially removing the requirement of spectroscopic observations to acquire similar ...
Murphy, Simon J.
core  

New periodic variable stars coincident with ROSAT sources discovered using SuperWASP [PDF]

open access: yes, 2007
We present optical lightcurves of 428 periodic variable stars coincident with ROSAT X-ray sources, detected using the first run of the SuperWASP photometric survey. Only 68 of these were previously recognised as periodic variables.
West, Richard G.   +75 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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