Results 81 to 90 of about 1,877,657 (298)

Start-up story: Penelope

open access: yesInsights: The UKSG Journal, 2017
James Harwood is the founder of Penelope, an automated tool that checks manuscripts and gives immediate feedback to authors before they submit to a journal.
James Harwood
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The KfW/ZEW start-up panel: design and research potential [PDF]

open access: yes
So far, there has been no data set which observes firm formations in Germany not only on a cross-sectional basis using one-time surveys, but continuously over a number of years. Therefore, the Centre for European Economic Research (ZEW), KfW Bankengruppe
Fryges, Helmut   +2 more
core   +3 more sources

Do profitable start-up firms grow faster? Evidence from Colombia

open access: yesCuadernos de Economía, 2018
This study explores the impact of profitability on the growth of start-up firms. Using data on start-up firms in Colombia, we examine the relationship between firm growth and profitability.
Yuji Honjo
doaj   +1 more source

Labour Market Performance and Start-Up Costs: OECD Evidence [PDF]

open access: yes
This paper is intended to make a contribution to the empirical literature explaining the rise ofunemployment since the 1970s in western economies by means of interactions betweenshocks and institutions. The contribution is twofold. First, the impact of a
Paloma Lopez-Garcia
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PhotoMonitoring: la fotografia digitale come strumento di monitoraggio

open access: yesGEOmedia
Just under five years ago it seemed impossible to be able to use a simple and already widespread camera as a reliable monitoring tool for a design engineer.
Antonio Cosentino   +2 more
doaj   +2 more sources

Fair Business Leadership: Is Protecting Minority Investors Important to the Development of Start-Ups in Clean and Digital Energy? [PDF]

open access: yesBusiness Ethics and Leadership
The protection of minority investors is increasingly recognized as crucial for the growth of start-ups in the clean and digital energy sectors, which are central to advancing global sustainability goals. Start-ups in these sectors face unique challenges,
Dmytro Halynskyi, Oleksandr Telizhenko
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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