Results 141 to 150 of about 391,562 (301)

A Fellowship Approach to Accelerating Social Entrepreneurs [PDF]

open access: yes, 2016
When Echoing Green, a nonprofit focused on unleashing next-generation talent, was founded in 1987, the term "social entrepreneur" was not widely used. Emerging leaders who wanted to change the world had limited options to access capital and programmatic ...
Andrea Davila, Min Pease
core  

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

open access: yesAdvanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang   +4 more
wiley   +1 more source

Entrepreneurship ecosystem evolution strategy of Saudi Arabia

open access: yesPrzedsiębiorczość Międzynarodowa, 2016
In majority of times when a potential start-up strikes a brilliant business idea, he/she has little knowledge of ‘how to move from there’. They lack information on the stakeholders of entrepreneurship ecosystem who can help and assist these startups in ...
Muhammad Rahatullah Khan
doaj   +1 more source

Contributions of sustainable start-up ecosystem to dynamics of start-up companies: the case of Lithuania

open access: yesEntrepreneurship and Sustainability Issues, 2015
Mindaugas Laužikas   +3 more
doaj   +1 more source

Cancer‐Associated Fibroblasts Promote Tumor Immunosuppression in Hepatocellular Carcinoma via the NNMT‐ANGPTL4 Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu   +20 more
wiley   +1 more source

Investing in People [PDF]

open access: yes, 2015
Foundations have long created programs to provide grants to individuals—most often in the form of fellowships, scholarships, and prizes. Several of these programs have become so prominent that they are now institutions in and of themselves. Consider just
Elizabeth Thompson, Patricia Patrizi
core  

Chemically Engineered L. reuteri Delivering αPD‐L1 and Gallium Ions via Metal‐Phenolic Networks Potentiate Anti‐Tumor Immunity and Ferroptosis

open access: yesAdvanced Science, EarlyView.
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang   +7 more
wiley   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

open access: yesAdvanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao   +3 more
wiley   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

open access: yesAdvanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin   +12 more
wiley   +1 more source

Start up ecosystem: Features, processes, and actors.

open access: yes, 2021
Successful start-ups can positively contribute to the well-being of countries' economies by creating jobs and new investment opportunities. The success of start-ups strongly depends on the ecosystem in which they are inserted. In this regard, it is important to understand the concept of the start-up ecosystem, in particular from the point of view of ...
openaire   +1 more source

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