ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysisâmediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
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Kujala K, Kinnunen V.
europepmc +1 more source
Enhancing microbial safety and flavor of fermented peppers through inoculation of distinct lactic acid bacteria and yeasts. [PDF]
Chen Z, Tang X, Liu W, Shen Y, Luo Y.
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Wang H +12 more
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Chen H +5 more
europepmc +1 more source
An ethics-informed computable audit framework for monitoring misdiagnosis risk in AI-assisted diagnosis. [PDF]
Li Y +6 more
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Zhang R, Gasparini S, Geerling JC.
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