Results 71 to 80 of about 1,242,659 (298)

Directed transport as a mechanism for protein folding in vivo

, 2009
We propose a model for protein folding in vivo based on a Brownian-ratchet mechanism in the multidimensional energy landscape space. The device is able to produce directed transport taking advantage of the assumed intrinsic asymmetric properties of the ...
Alberts B., Bhutani N., Ellis R. J., Ernesto González-Candela, Kramer G., Lapanje S., Levinthal C., van Kampen N. G., Visscher K., Víctor Romero-Rochín   +9 more
core   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

First-Principles Based Matrix-Green's Function Approach to Molecular Electronic Devices: General Formalism

, 2001
Transport in molecular electronic devices is different from that in semiconductor mesoscopic devices in two important aspects: (1) the effect of the electronic structure and (2) the effect of the interface to the external contact. A rigorous treatment of
Albright, Andersen, Aulbur, Aviram, Baerends, Bormet, Brivio, Büttiker, Büttiker, Caroli, Chelikowsky, Chen, Collier, Danielewicz, Datta, Datta, Dederichs, Dekker, Di Ventra, Dorogi, Dreizler, Elstner, Emberley, Emberley, Feibelman, Feibelman, Ferrante, Ferry, Feynman, Frisch, Gimzewski, Goldhaber-Gordon, Goringe, Gross, Gunnarson, Hall, Haug, Hedin, Hershfield, Hirose, Hoffmann, Hoffmann, Joachim, Joachim, Joachim, Jones, Kadanoff, Keldysh, Kruger, Lake, Landauer, Lang, Lang, Lang, Lang, Lang, Lang, Langreth, Larade, Lundstrom, Lyo, Magoga, Mark A. Ratner, McWeeny, Meir, Meir, Metzger, Mujica, Mujica, Ness, Nitzan, Parr, Perdew, Petrov, Pople, Porath, Reed, Reed, Saito, Scheffler, Stowasser, Supriyo Datta, Tans, Taylor, Tian, Trioni, Wachutkal, Wan, Williams, Wilson, Xue, Xue, Xue, Yaliraki, Yongqiang Xue, Zeller   +95 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Design and Simulation Analysis for Double Globoidal Cam-type ATC Device based on RecurDyn

Jixie chuandong, 2016
As the key component of machining center,the structure and driving mode of ATC device directly influence the time and efficiency of tool changing. Starting from the structure and principle of the cam-type ATC device,based on the theory of globoidal cam ...
Ge Zhenghao, Li Sen, Si Xianyong, Cao Peng   +3 more
doaj  

SHOCK PROTECTION DEVICE FOR ROTATION SENSORS [PDF]

Fiabilitate şi Durabilitate, 2011
Starting form a virtual model of a device designed to investigate friction force effects in colliding mechanical systems, the authors have developed a test-rig. The friction force effects had to be estimated using a rotating sensor.
Stelian ALACI, Florina Carmen CIORNEI, Dumitru AMARANDEI, Constantin FILOTE, Simion PĂTRAŞ-CICEU, Dorel PRODAN   +5 more
doaj  

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Sorption-induced Static Bending of Microcantilevers Coated with Viscoelastic Material [PDF]

, 2008
Absorption of a chemical analyte into a polymercoating results in an expansion governed by the concentration and type of analyte that has diffused into the bulk of the coating.
Datskos, P. G., Heinrich, Stephen M., Josse, Fabien, Wenzel, Michael J., Yaz, Edwin E   +4 more
core   +1 more source

Boosting the voltage gain of graphene FETs through a differential amplifier scheme with positive feedback

, 2014
We study a possible circuit solution to overcome the problem of low voltage gain of short-channel graphene FETs. The circuit consists of a fully differential amplifier with a load made of a cross-coupled transistor pair.
Baccarani, Giorgio, Di Lecce, Valerio, Gnani, Elena, Gnudi, Antonio, Grassi, Roberto, Reggiani, Susanna   +5 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source