Results 101 to 110 of about 4,863,810 (270)

A Language‐Guided Multimodal Foundation Model for Zero‐Shot and Multi‐Task Brain Signal Analysis

Advanced Intelligent Systems, EarlyView.
METIS aligns brain signals with natural‐language instructions to enable zero‐shot and multi‐task brain signal analysis. Pretrained on over 70 000 h of EEG and iEEG recordings, it generalizes across sleep stage classification, epilepsy detection, and neurological disorder diagnosis, providing a scalable foundation model for clinically meaningful brain ...
Mingzhi Chen, Yiyu Gui, Guibo Luo, Yuchao Yang   +3 more
wiley   +1 more source

Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor [PDF]

, 1994
The receptor for the inhibitory neurotransmitter glycine is a member of the ligand gated ion channel recep tor superfamily. Point mutations in the gene encoding the alpha 1 subunit of the glycine receptor channel complex (GlyR) have recently been ...
Rajendra, Sundran, Lynch, Joseph W., Barry, Peter H., French, Chris R., Schofield, Peter R., Pierce, Kerrie D.   +5 more
core  

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Synergistic Advanced Oxidation and Physicochemical Treatment Strategies for Antibiotic Removal and Resistance Mitigation in Water

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The presence of antibiotics in water not only causes environmental pollution but also increases the growth of antibiotic‐resistant bacterial genes, which pose serious threats to human beings and other water residents. Large numbers of people are reportedly affected by the resistant bacterial genes, as many broad‐spectrum antibiotics are not ...
Amir Zada, Shohreh Azizi
wiley   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

CTNNB1-related disorders: clinical and radiological contributions from a French cohort

Frontiers in Neurology
CTNNB1 monoallelic pathogenic variants account for up to 4% of genetically determined cerebral palsy cases, yet their phenotypic spectrum remains poorly defined.
Eline Chauvet-Piat, Eline Chauvet-Piat, Marie-Céline François-Heude, Gaël Manes, Arthur Coget, Nicolas Leboucq, Bérénice Lecardonnel, Heidy Baide-Mairena, Marine Allais, Souad Touati, Stéphanie Sanchez, Mirna Khalil, Hugues Chevassus, Marjolaine Willems, Marjolaine Willems, Marjolaine Willems, Marjolaine Willems, David Geneviève, Marion Serrand, Laure Mazzola, Laure Mazzola, Vincent Dubard, Mathilde Renaud, Mathilde Renaud, Mathilde Renaud, Caroline Le Camus, Rebecca More, Mathieu Milh, Caroline Paris, Ians-Bouteiller Cécile, Agathe Roubertie, Agathe Roubertie, Agathe Roubertie   +32 more
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

Mathematical modeling of the spread of the coronavirus under strict social restrictions

Mathematical Methods in the Applied Sciences, EarlyView., 2021
We formulate a simple susceptible‐infectious‐recovery (SIR) model to describe the spread of the coronavirus under strict social restrictions. The transmission rate in this model is exponentially decreasing with time. We find a formula for basic reproduction function and estimate the maximum number of daily infected individuals.
Mo'tassem Al‐arydah, Hailay Berhe, Khalid Dib, Kalyanasundaram Madhu   +3 more
wiley   +1 more source

Data-Driven Insights into Hyperkinetic Disorders in Neurodevelopmental Syndromes and Epileptic Encephalopathies. [PDF]

Mov Disord Clin Pract
Abstract Background Childhood‐onset hyperkinetic movement disorders occur in a range of genetic conditions. Recently, there has been an increase in recognition of hyperkinetic movement disorders, mainly dystonia, chorea and dyskinesia, with monogenic conditions associated with neurodevelopmental delay (NDD) and also with developmental and epileptic ...
Morales-Briceño H, Mohammad SS, Angiti RR, Han V, Tchan M, Dale RC, Fung VSC.   +6 more
europepmc   +2 more sources

More‐than‐gender? Moving beyond gendered expectations of divergent learners in early childhood education

British Educational Research Journal, EarlyView.
Abstract In this paper, we explore how neurodivergent ways of being in early education are often gendered. The intersectionalities of gender and neurodivergence often lead to fixed expectations that perpetuate binary interpretations, pathologisations, missed diagnoses and a lack of curated support.
Ruth Churchill Dower, Hannah Hogarth
wiley   +1 more source