Results 41 to 50 of about 192,084 (260)

Regulation of the development of flight muscles in long-winged adults of the flightless bug Pyrrhocoris apterus (Heteroptera: Pyrrhocoridae)

European Journal of Entomology, 2008
We studied the development of the indirect flight muscles and reproductive organs in long-winged (macropterous) adults of the flightless bug Pyrrhocoris apterus (L.) and the factors involved in flight muscles histolysis by means of total protein analysis.
Radomír SOCHA, Jan ŠULA
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Adaptive Physiological and Morphological Adjustments Mediated by Intestinal Stem Cells in Response to Food Availability in Mice

Frontiers in Physiology, 2019
Several studies have evaluated plastic changes in the morphology of the digestive tract in rodents subjected to caloric restriction or restricted availability.
Isaac Peña-Villalobos, Isaac Peña-Villalobos, Ignacio Casanova-Maldonado, Pablo Lois, Pablo Sabat, Pablo Sabat, Verónica Palma   +6 more
doaj   +1 more source

Starvation and refeeding influence the growth, biochemical index, intestinal microbiota, and transcriptomic profiles of golden pompano Trachinotus ovatus (Linnaeus 1758)

Frontiers in Marine Science, 2022
Starvation is a common stress in fish that is caused by environmental changes, and refeeding after starvation is believed to cause compensatory growth.
Bo Liu, Bo Liu, Hua-Yang Guo, Hua-Yang Guo, Hua-Yang Guo, Bao-Suo Liu, Bao-Suo Liu, Bao-Suo Liu, Bao-Suo Liu, Nan Zhang, Nan Zhang, Nan Zhang, Jing-Wen Yang, Liang Guo, Liang Guo, Liang Guo, Shi-Gui Jiang, Shi-Gui Jiang, Shi-Gui Jiang, Dian-Chang Zhang, Dian-Chang Zhang, Dian-Chang Zhang, Dian-Chang Zhang, Dian-Chang Zhang   +23 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The effect of running and starvation interventions on atherogenic index and Xbp1 gene expression in the endoplasmic reticulum of liver in non-alcoholic fatty liver rats [PDF]

Medical Laboratory Journal
Background: Running and starvation can have a positive effect on the reticulophagy of the liver tissue. The purpose of this research was to investigate the effect of running and starvation interventions on the atherogenic index and Xbp1 gene change in ...
Mahshad Paziraee, Habib Asgharpour, Asra Askari, Reza Rezaei Shirazi, Neda Aghaei Bahman Beglo   +4 more
doaj  

“From spoiling natives to no work, no food”: Food scarcity and the controversy of food rations during the South African War

Scientia Militaria, 2022
Food became scarce during the South African War (1899–1902), which led to large numbers of the population dying from starvation or diseases related to hunger. This was due to certain towns in the country being under siege, while farms and homesteads were
Mpho Manaka
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Sleep in Drosophila and Its Context

Frontiers in Physiology, 2019
A prominent idea emerging from the study of sleep is that this key behavioural state is regulated in a complex fashion by ecologically and physiologically relevant environmental factors. This concept implies that sleep, as a behaviour, is plastic and can
Esteban J. Beckwith, Alice S. French
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source