Results 21 to 30 of about 191,774 (262)
Biology, 2021 Hepatic steatosis caused by starvation, resulting in non-alcoholic fatty liver disease (NAFLD), has been a research topic of human clinical and animal experiments.
Hao Xu +5 more
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eLifeThe brain regulates food intake in response to internal energy demands and food availability. However, can internal energy storage influence the type of memory that is formed?
Michael Berger +5 more
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Frontiers in Physiology, 2019 The blood-brain barrier (BBB) is essential for the exchange of nutrient and ions to maintain the homeostasis of central nervous system (CNS). BBB dysfunction is commonly associated with the disruption of endothelial tight junctions and excess ...
Zhenguo Yang +6 more
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Complex Ecotype Dynamics Evolve in Response to Fluctuating Resources
mBio, 2022 Ecotypic diversification and its associated cooperative behaviors are frequently observed in natural microbial populations whose access to resources is often sporadic.
Megan G. Behringer +7 more
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Frontiers in Immunology, 2022 As the goal of a bacterium is to become bacteria, evolution has imposed continued selections for gene expression. The intracellular pathogen Mycobacterium tuberculosis, the causative agent of tuberculosis, has adopted a fine-tuned response to survive its
Catherine Vilchèze +5 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Anais da Academia Brasileira de Ciências, 2008 The present study investigated whether the callianassid Callichirus major shows a lecithotrophic behaviour during larval development. Two experiments were carried out.
Fernando A. Abrunhosa +3 more
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Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Elevated plasma levels of the appetite-stimulator ACBP/DBI in fasting and obese subjects
Cell Stress, 2021 Eukaryotic cells release the phylogenetically ancient protein acyl coenzyme A binding protein (ACBP, which in humans is encoded by the gene DBI, diazepam binding inhibitor) upon nutrient deprivation. Accordingly, mice that are starved for one to two days
Sijing Li +3 more
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