Results 251 to 260 of about 273,588 (361)

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Celastrol ameliorates atherosclerosis by inhibiting TLR4/STAT3/NLRP3-mediated macrophage pyroptosis. [PDF]

Chin Med
Shi Y, Li Z, Liu Q, Qiu Y, Long J, Yang Q, Zhang C, Gong Y, Qin L.   +8 more
europepmc   +1 more source

STAT3 Measurement [PDF]

, 2020
openaire   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

STAT3 inhibitor in oncology: a trial-based analysis of translational challenges and evolving therapeutic paradigms. [PDF]

Front Oncol
Yang S, Wang L, Chuan Z, Nie J.
europepmc   +1 more source

Serum Proteomic Signatures of Rheumatoid Arthritis Risk and Response: Analysis of a Rheumatoid Arthritis Interception Trial

Arthritis &Rheumatology, EarlyView.
Objective Our study objective was to identify serum protein signatures associated with progression to rheumatoid arthritis (RA) and response to abatacept in at‐risk individuals. Methods A total of 440 serum samples from 118 APIPPRA (Arthritis Prevention In the Preclinical Phase of RA with Abatacept) study participants were selected from baseline to RA ...
Marianna Jasenecova, Carl Coyle, Alina Mihalovits, Sarah Ryan, Elizabeth Pook, Esperanza Perucha, Gabrielle Harker, Melody Chin, Sam Norton, Andrew P. Cope   +9 more
wiley   +1 more source

ROP16 Promotes Epithelial-Mesenchymal Transition-Like Changes in Ocular Toxoplasmosis via STAT3 and TGF-β1 Pathways. [PDF]

Transbound Emerg Dis
Song L, Xu L, Liu Y, Yang Y, Wang C, Zhang Y, Luo Q, Cao Y, Wang Y, Yu L.   +9 more
europepmc   +1 more source

Long Noncoding RNA H19 Mediates STAT3‐Dependent Activation of Keratinocytes and Fibroblasts in Systemic Sclerosis Skin

Arthritis &Rheumatology, EarlyView.
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz, Christopher W. Wasson, Rebecca L. Ross, Francesco Del Galdo   +3 more
wiley   +1 more source

Anticancer Effects of <i>Clausena hamandiana</i>: Ethanolic Extract Inhibits Cancer Cell Proliferation and Suppresses Lung Tumorigenesis in Mice. [PDF]

Int J Mol Sci
Boonyarat C, Hayakawa Y, Samar N, Vanichakulthada N, Kaewamatawong R, Supapaan TS, Sethabouppha B, Waiwut P.   +7 more
europepmc   +1 more source

STAT3 Deficiency [PDF]

, 2020
openaire   +1 more source