Results 61 to 70 of about 2,190,945 (258)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
IEEE AccessAccurate target tracking is essential for the effectiveness of air surveillance, air-traffic monitoring, and defense-support systems. This paper presents a comparative study of several dynamic motion models applied to Kalman-based filters for aerial ...
Arthur Medeiros Macedo +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
State space modelling of extreme values with particle filters [PDF]
, 2009 State space models are a flexible class of Bayesian model that can be used to smoothly capture non-stationarity. Observations are assumed independent given a latent state process so that their distribution can change gradually over time. Sequential Monte
Wyncoll, David P.
core
International Journal for Re-Views in Empirical Economics, 2018 In 2002 we published a paper in which we used state space time series methods to analyse the teenage employment-federal minimum wage relationship in the US (Bazen and Marimoutou, 2002).The study used quarterly data for the 46 year period running from ...
Velayoudom Marimoutou, Stephen Bazen
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Sequential Monte Carlo methods for parameter estimation in nonlinear state-space models
, 2012 Stochastic nonlinear state-space models (SSMs) are prototypical mathematical models in geoscience. Estimating unknown parameters in nonlinear SSMs is an important issue for environmental modeling.
Zhang, Hui, Gao, Meng
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Bayesian Inference of Hidden Cognitive Performance and Arousal States in Presence of Music
IEEE Open Journal of Engineering in Medicine and BiologyGoal: Poor arousal management may lead to reduced cognitive performance. Specifying a model and decoder to infer the cognitive arousal and performance contributes to arousal regulation via non-invasive actuators such as music.
Saman Khazaei +3 more
doaj +1 more source