Results 81 to 90 of about 34,520,301 (258)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subspace system identification
Iranian Journal of Electrical and Electronic Engineering, 2005 We give a general overview of the state-of-the-art in subspace system identification methods. We have restricted ourselves to the most important ideas and developments since the methods appeared in the late eighties.
J. Poshtan, H. Mojallali
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
IEEE Access, 2019 The autonomic nervous system (ANS) stimulates various sweat glands for maintaining body temperature as well as in response to various psychological events. Variations in skin conductance (SC) measurements due to salty sweat secretion can be used to infer
MD. Rafiul Amin, Rose T. Faghih
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Modal identification of bridge systems using state‐space methods
, 2005 Arrays of large numbers of sensors and accompanying complex system identification (SI) methods have been recently used in engineering applications on structures ranging from complex real space trusses to simple experimental beams.
Y. Arici, K. Mosalam
semanticscholar +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
State space analysis of diphtheria pathogenesis using semi-tensor products and permutation methods [PDF]
Network BiologyIn this study, we analyze the state space of a Boolean network modeling diphtheria pathogenesis, focusing on key genes such as Tox, Rep, INF1/INF2, TLR, AP1, IL6, and TNF.
Ugbene Ifeanyichukwu Jeff +1 more
doaj
Linear Offset-Free Model Predictive Control in the Dynamic PLS Framework
Information, 2018 This work addresses the model predictive control (MPC) of the offset-free tracking problem in the dynamic partial least square (DyPLS) framework. Firstly, state space MPC based on the DyPLS is proposed.
Ligang Hou, Ze Wu, Xin Jin, Yue Wang
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source