Results 221 to 230 of about 29,169,368 (250)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

m⁶A modification in immune-cell inflammatory fate: from RNA fate regulation to therapeutic translation in inflammatory diseases. [PDF]

Front Immunol
Zhu Y, Yang S, Qin L, Ding D, Gan X.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy. [PDF]

Adv Sci (Weinh)
Lin Y, Dai M, Dai E, Kang R, Klionsky DJ, Tang D, Sun Y, Lv N, Jiang J.   +8 more
europepmc   +1 more source

Computational modeling of substrate-dependent lung mitochondrial respiration and bioenergetics in rats with different susceptibility to hyperoxia-induced ARDS. [PDF]

Am J Physiol Cell Physiol
Taheri P, Dave DD, Clough AV, Dash RK, Audi SH.   +4 more
europepmc   +1 more source

Non-canonical activation of VEGFA through TIMM44-dependent mitochondrial remodelling. [PDF]

Redox Biol
Chaudhary T, Bhat SM, Pradhan P, Joshi MB, Sinha D.   +4 more
europepmc   +1 more source

Macrophage states and polarization during <i>Mycobacterium tuberculosis</i> infection: mechanisms, granuloma adaptation, and host-directed therapeutic opportunities. [PDF]

Front Cell Infect Microbiol
Xu M, Peng Z.
europepmc   +1 more source