Results 121 to 130 of about 172,436,842 (252)

Smoking and state of health. [PDF]

open access: yesBMJ, 1985
R, Balarajan, P, Yuen, B R, Bewley
openaire   +2 more sources

Biennial report of the State Board of Health of California for the years of ... and ...

open access: yes, 1884
No report printed for 1896 ... 1898.Reports for -1924 ... 1926 cover period from July 1 to June 30.Mode of access: Internet.With vol. for 1926 ... 1928 continued by: California. Dept. of Public Health.
California State Board of Health.
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Health-related quality of life and well-being health state values among Dutch oldest old

open access: yesPatient Preference and Adherence, 2019
Riaan Botes,1 Karin M Vermeulen,1 Anthonie M Gerber,2 Adelita V Ranchor,3 Erik Buskens11Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, 9700 RB, The Netherlands; 2Department of Basic Medical Sciences ...
Botes R   +4 more
doaj  

Annual report of the State Board of Health and Bureau of Vital Statistics of Missouri.

open access: yes, 1914
Title varies slightly.Mode of access ...
Missouri. Bureau of Vital Statistics.   +1 more
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Regulations and technical standards for subsurface sewage disposal systems

open access: yes, 2004
Cover title.; "Section 19-13-B100a (Building Conversions, Changes in Use, Additions), Effective August 3, 1998, Section 19-13-B103 (Discharges 5,000 Gallons Per Day or Less), Effective August 16, 1982, Technical Standards (Pursuant to Section 19-13-B103),
Connecticut. Dept. of Public Health.
core   +1 more source

In the shadow of exclusion: the state of New Zealand Asian health

open access: yesNew Zealand Medical Student Journal, 2019
New Zealand (NZ) Asians have a long history in Aotearoa dating back to the 19th century, with especially pronounced increases in migration over the past few decades. This ethnic category is an exceptionally broad term, which incorporates individuals with
Rex Liao
doaj  

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