Results 131 to 140 of about 2,446,518 (308)

LT-YOLO: long-term temporal enhanced YOLO for stenosis detection on invasive coronary angiography

open access: yesFrontiers in Molecular Biosciences
Coronary artery stenosis detection by invasive coronary angiography plays a pivotal role in computer-aided diagnosis and treatment. However, it faces the challenge of stenotic morphology confusion stemming from coronary-background similarity, varied ...
Jiaxin Li, Xiang Tang, Xuesong Wang
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A Fast SOC Balancing Method for MMC-BESS Based on Nonlinear Model-Predictive Control

open access: yesEnergies
In modular multilevel converter battery energy storage systems (MMC-BESS), state-of-charge (SOC) balancing is essential for ensuring safe and reliable operation.
Xiaofan Ji   +5 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Fault Signal Emulation of Marine Turbo-Rotating Systems Based on Rotor-Gear Dynamic Interaction Modeling

open access: yesJournal of Marine Science and Engineering
Rotating machinery is essential in various industrial fields, and growing demands for high performance under harsh operating conditions have heightened interest in fault diagnosis and prognostic technologies. However, a major challenge in fault diagnosis
Seong Hyeon Kim   +4 more
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

A non-gaussian continuous state space model for asset degradation

open access: yes, 2008
The degradation model plays an essential role in asset life prediction and condition based maintenance. Various degradation models have been proposed.
Mathew, Joseph, Ma, Lin, Zhou, Yifan
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Forecasting Australian Macroeconomic variables, evaluating innovations state space approaches

open access: yes
Innovations state space time series models that encapsulate the exponential smoothing methodology have been shown to be an accurate forecasting tool. These models for the first time are applied to Australian macroeconomic data.
de Silva, Ashton J
core  

An Assessment of Alternative State Space Models for Count Time Series [PDF]

open access: yes
This paper compares two alternative models for autocorrelated count time series. The first model can be viewed as a 'single source of error' discrete state space model, in which a time-varying parameter is specified as a function of lagged counts, with ...
Ralph D. Snyder   +3 more
core  

Home - About - Disclaimer - Privacy