Results 91 to 100 of about 1,472,346 (301)

Stochastic Period and Cohort Effect State-Space Mortality Models Incorporating Demographic Factors via Probabilistic Robust Principal Components

Risks, 2017
In this study we develop a multi-factor extension of the family of Lee-Carter stochastic mortality models. We build upon the time, period and cohort stochastic model structure to extend it to include exogenous observable demographic features that can be ...
Dorota Toczydlowska, Gareth W. Peters, Man Chung Fung, Pavel V. Shevchenko   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Impact of Short-Circuit Ratio on Control Parameter Settings of DFIG Wind Turbines

Energies
This work deals with doubly fed induction generator (DFIG) modeling and stability when connected to weak AC grids. A detailed state-space model that includes the phase-locked loop (PLL) is developed.
Joaquín Pedra, Luis Sainz, Lluís Monjo
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

AMSRDet: An Adaptive Multi-Scale UAV Infrared-Visible Remote Sensing Vehicle Detection Network

Sensors
Unmanned Aerial Vehicle (UAV) platforms enable flexible and cost-effective vehicle detection for intelligent transportation systems, yet small-scale vehicles in complex aerial scenes pose substantial challenges from extreme scale variations ...
Zekai Yan, Yuheng Li
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Integrating behavioral movement and environmental preferences to map critical habitat of whale sharks using long-term satellite tracking in the Indo-Pacific Ocean

Frontiers in Marine Science
Understanding the spatial ecology of wide-ranging marine megafauna is essential for identifying critical habitats and designing effective conservation strategies.
Mochamad Iqbal Herwata Putra, Mochamad Iqbal Herwata Putra, Anindya Wirasatriya, Anindya Wirasatriya, Abraham Sianipar, Abdi Hasan, Edy Setyawan, Ismail Syakurachman, Ronald Mambrasar, Mark Erdmann, Jatna Supriatna, Masita Dwi Mandini Manessa   +11 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bootstrap prediction intervals in State Space models [PDF]

Prediction intervals in State Space models can be obtained by assuming Gaussian innovations and using the prediction equations of the Kalman filter, where the true parameters are substituted by consistent estimates.
Esther Ruiz, Alejandro Rodriguez
core  

Parameter estimation in sparse state-space models [PDF]

State-space models are a flexible framework for modelling sequential data in the presence of noise or incomplete observations, within which we model a system via a hidden state process and a related observation process.
Cox, Benjamin
core   +1 more source