Results 111 to 120 of about 1,472,346 (301)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Identification of speculative bubbles using state-space models with Markov-switching [PDF]
In this paper we use a state-space model with Markov-switching to detect speculative bubbles in stock-price data. Our two innovations are (1) to adapt this technology to the state-space representation of a well-known present-value stock-price model, and (
Bernd Wilfling, Nael Al-Anaswah
core
Multilevel State-Space Models Enable High Precision Event Related Potential Analysis. [PDF]
Conf Rec Asilomar Conf Signals Syst Comput, 2023 Das P, He M, Purdon PL.
europepmc +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Bidirectional Mamba-Enhanced 3D Human Pose Estimation for Accurate Clinical Gait Analysis
Fractal and FractionalThree-dimensional human pose estimation from monocular video remains challenging for clinical gait analysis due to high computational cost and the need for temporal consistency.
Chengjun Wang +3 more
doaj +1 more source
The Relationship between Inflation and Inflation Uncertainty in the Short- and Long-run: State Space Models with Markov Regime Switching Heteroskedasticity [PDF]
فصلنامه پژوهشهای اقتصادی ایران, 2013 In this study by using Markov Regime Heteroscedasticity method (MRSH) In the form of state-space model the relationship between inflation and uncertainty of inflation in Iranian economics is examined.
Reza Najarzadeh +2 more
doaj
Combining multiple data sources with different biases in state-space models for population dynamics. [PDF]
Ecol Evol, 2023 Polansky L, Mitchell L, Newman KB.
europepmc +1 more source