Results 101 to 110 of about 1,582,558 (310)

The imperative of state capacity in public health crisis: Asia's early COVID-19 policy responses. [PDF]

Governance (Oxf), 2022
Yen WT, Liu LY, Won E, Testriono.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Paradoxes of inter-municipal public consortia in Brazil: do state capacities and social accountability in municipalities influence their decisions to cooperate?

Revista Iberoamericana de Estudios Municipales
Brazilian literature on intergovernmental cooperation to formulate and deliver public policies (referred here as “inter-municipal public consortia”), suggests a lack of managerial quality and social accountability in these arrangements.
Eduardo José Grin, Gustavo Fernandes
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Capacity-testing as a means of increasing political inclusion

, 2012
Some competent political actors, primarily young people and the cognitively impaired, are excluded from political participation by modern liberal democratic states.
Munn, Nicholas
core   +1 more source

Denunciar violencia de pareja en Chile: Aspectos a considerar desde el Aparato Estatal

Sortuz, 2022
El presente ensayo analiza el actuar del Estado Chileno para facilitar las condiciones necesarias para que las personas ejerzan su derecho a denunciar actos de violencia en el contexto de pareja, cuando han sido víctimas de ello.
Juan Paulo Marchant Espinoza
doaj  

The impact of state capacity on the cross-country variations in COVID-19 vaccination rates. [PDF]

Int J Health Econ Manag, 2022
Tevdovski D, Jolakoski P, Stojkoski V.
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mission Green: Defense, Decarbonization, and the Politics of Transformative Mission‐Oriented Innovation Policy

Politics and Governance
The urgency of decarbonization has generated increasing interest in using mission-oriented innovation policies to achieve net-zero emissions. An energy transformation, however, requires managing a much more complex portfolio of supply- and demand-side ...
Carlos Cantafio Apitz, Darius Ornston, Trang Thu Nguyen   +2 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source