Results 81 to 90 of about 1,582,558 (310)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 2021 In the USA, responsibility for sustainable urban development and conservation planning falls primarily on local governments and other local agencies. Often, municipalities that do act have been commanded or incentivized by federal or state governments.
Carpenter, Vincent
core +2 more sources
Globalization & State Capacity in Africa
Procedia - Social and Behavioral Sciences, 2010 AbstractThe paper examines the impact of globalization on state capacity in Africa. It problematizes globalization as a central determining factor in building the capable state in Africa. Globalization, although it requires typologizing and contextualizing or historicizing, is used to refer to a complex set of interconnected multi-linear, multifaceted ...
openaire +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
, 2015 The South Carolina Office of the State Treasurer annually publishes reports on the annual state debt and local government debt. The state debt report provides an overview and summary of the state debt limitations, constraints, and ...
South Carolina Office of the State Treasurer
core
Capacity Markets for Electricity [PDF]
, 2003 The creation of electricity markets has raised the fundamental question as to whether markets provide the right incentives for the provision of the reserves needed to maintain system reliability, or whether some form of regulation is needed.
Creti, Anna, Fabra, Natalia
core
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Under-investment in state capacity: the role of inequality and political instability [PDF]
Existing studies have shown that the state's ability to tax, also known as fiscal capacity, is positively related to economic development. In this paper, we analyze the determinants of the government's decision to invest in state capacity, which involves
Mauricio Cárdenas, Didem Tuzemen
core
Who wants violence? The political economy of conflict and state building in Colombia
Cuadernos de Economía, 2019 I propose three broad sets of political economy underpinnings for the persistence of conflict and the weak state. First, a “public goods trap” rooted in inequality implies that a low supply of, and demand for, public goods reinforce each other.
Leopoldo Fergusson
doaj +1 more source