Results 61 to 70 of about 1,582,558 (310)
State Capacity: Utilization, Durability, and the Role of Wealth vs. History
RIMCIS, 2012 The concept of state capacity has been in development literature for decades. Nevertheless the concept, its operationalization, and its measurement are still highly contested.
Elaine Enriquez, Miguel Angel Centeno
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Social Investment and State Capacity. CEPS Working Document No. 419/February 2016 [PDF]
, 2016 This paper looks at the difference between the levels and nature of social policy expenditure in northern and northwest European countries and the countries of southern, central, and eastern Europe, and examines the relationship between social investment
Beblavý, Miroslav, Hájková, Alžbeta
core
Frontiers in Political ScienceE-government is a prominent approach in environmental sustainability as it brings various arrangements that allow for the mitigation of greenhouse gas emissions. The article explores two main objectives.
Lloyd George Banda +2 more
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Good Governance through Public Policy Education: Experiences from US-Mexico and Iran-Afghanistan Water Treaties [PDF]
Iranian Journal of International and Comparative LawThe inherent difficulties of designing and executing good public policy are not restricted to modernity or any specific political system. Many of these difficulties were pondered and discussed even in the ancient world.
Clay Ramsay, Javad Arabshirazi
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Generative AI‐Making and State‐Making: Sovereign AI Race and the Future of Digital Geopolitics
Politics and GovernanceThis article examines how intensifying global competition for sovereign AI, fueled by the rise of generative AI, is reshaping state capacity and digital geopolitics.
Zhenyu Wang
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