Results 71 to 80 of about 1,582,558 (310)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

STRATEGIC COORDINATION AND POLICY CAPACITY: EXECUTIVE INSTITUTIONS AS DRIVERS OF GOVERNANCE INNOVATION IN ARMENIA

open access: yesBanber Erevani Hamalsarani. Sots'iologia
This article examines the transformation of executive institutions in the Republic of Armenia through the lens of political sociology, viewing them not merely as administrative structures but as arenas of struggle for symbolic and material capital ...
Marina Margaryan
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

State capacity, manufacturing and civil conflict [PDF]

open access: yes
In this note we empirically analyze the link between state capacity and civil conflict via the manufacturing sector, which is the source of wealth for emerging new elite interested in obtaining political representation, and is the outcome of a new ...
Roberto Ricciuti, Jacopo Costa
core  

Models of verbal working memory capacity: What does it take to make them work? [PDF]

open access: yes, 2012
Theories of working memory (WM) capacity limits will be more useful when we know what aspects of performance are governed by the limits and what aspects are governed by other memory mechanisms.
Saults, J. Scott   +7 more
core   +1 more source

Does quantity mean quality? Comparing evidence of bureaucratic capacity and performance between agency groups in Brazil [PDF]

open access: yesRevista de Administração Pública
This article aims to assess whether the Brazilian government’s preference for enhancing the power and scope of its regulatory agencies compared to its non-regulatory agencies has led to proportional gains in terms of capacity and performance.
Bruno Queiroz Cunha, Pedro Cavalcante
doaj   +1 more source

Capacity of channels with action-dependent states

open access: yes2009 IEEE International Symposium on Information Theory, 2009
We consider channels with action-dependent states: Given the message to be communicated, the transmitter chooses an action sequence that affects the formation of the channel states, and then creates the channel input sequence based on the state sequence.
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

A Comparative Study on Land Reform in North Korea and North Vietnam: The Impact of Colonial Legacy and State Capacity

open access: yesThe Korean Journal of International Studies
This study examines how structural components—state capacity, social structure, and political context—shaped land reform in North Korea and North Vietnam.
doaj   +1 more source

The transformative capacity of the Brazilian federal government in building a social welfare bureaucracy in the municipalities

open access: yesRevista de Administração Pública, 2018
The article analyzes the transformative capacity of the Ministry of Social Development and Fight against Hunger (MDS) in shaping structural change in Brazilian municipalities.
Natália Guimarães Duarte Sátyro   +1 more
doaj   +2 more sources

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