Results 51 to 60 of about 1,582,558 (310)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
State Capacity and Health Outcomes: An Empirical Analysis [PDF]
Pakistan Journal of Commerce and Social Sciences, 2017 The purpose of this study is to analytically explore and empirically test the relationship of state capacity with health outcomes using cross sectional and panel datasets of 156 countries from 1970 to 2015.
Muhammad Tariq Majeed
doaj
SSRN Electronic Journal, 2023 Canonical studies of the origins of state capacity have focused on macro-historical or structural explanations. I review recent research in historical political economy that showcases the role of politics—agents, their constraints, and their motivations—in the evolution of state capacity.
openaire +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Humanities & Social Sciences CommunicationsThis article examines the linguistic landscapes (LL) of two communities in Beijing, China, to investigate the agency and structure embodied in them.
Mengli Zhang, Tianwei Zhang
doaj +1 more source
The Problems of Assessing Validity and Political Potential of Cross-National Comparative Ratings
Сравнительная политика, 2020 The author carries out a correlation analysis of positions of 145 countries in 16 comparative rating studies highly cited in social and political science and calculates the coefficient of their correlation with the positions of the Russian Federation ...
V. G. Ivanov
doaj +1 more source
Religious practice social changes during the COVID-19 pandemic in the United Arab Emirates.
Әл-Фараби Атындағы Қазақ Ұлттық Университеті хабаршы шығыстану сериясы, 2021 This article discusses some theoretical aspects of nation-building in the case of the United Arab Emir-ates and the social changes produced by COVID-19. Countries across the world responded very differently in their prevention and control of coronavirus ...
B. Myrzabekova
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2013 We argue that the regional threat environment a state faces plays a consequential role in its political development and the likelihood of experiencing future intrastate wars.
Miller, Steven V., Gibler, Douglas M.
core +1 more source