Results 101 to 110 of about 432,276 (266)

Model of situational quality management of preparation of pupils to unified state examination on computer science

RUDN Journal of Informatization in Education, 2012
Given article is devoted to working out of model of situational quality management of training pupils on computer science. Functions of quality management of preparation of pupils to examination, and as stages of model, actions of corresponding stages ...
S A Zhdanov, A P Silchenko
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

About Organizing Practical Training of Future Specialists at Scientific and Research Institute of Informational Technologies of Kherson State University

Ìнформаційні технології в освіті, 2008
In the report the Research Institute of Information Technologies of Kherson State University operational experience is expounded in practical students’ preparation of specialty “Applied mathematics. Computer Science”.
M. S. Lvov
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

THE USE OF «CLOUD COMPUTING» IS AT HIGHER SCHOOL

Ìнформаційні технології в освіті, 2013
To improve the training process is necessary to use such powerful technologies, as ‘cloud computing’. Supporting traditional training forms, it’s the new epoch of education development.
T. Arkhipova, T. Zaytseva
doaj  

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

About the problems of teaching future teacher-trainers in the condition of informatization of education

RUDN Journal of Informatization in Education, 2014
In this article are considered actuality of informatization of professional education, about problems of readiness to use information and computer technology of professional activity of future teacher-trainers.
B K Mukhamedzhanov, K M Berkimbaev, B Z Abuseitov, B S Omarov   +3 more
doaj  

We are entering a new era of problems: AI-generated images in research manuscripts

Oral Oncology Reports
This editorial highlights the significant threat of image fraud that may arise from the use of artificial intelligence (AI) generative technology in academic articles, which has been overlooked.
Kabir Suman Dash, Vini Mehta, Priyanka Kharat   +2 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source