Results 101 to 110 of about 3,141,228 (339)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Computer self-efficacy and motivation to use e-learning systems by LIS undergraduate students in Oyo State, Nigeria

open access: yesCybrarians Journal
This study investigated the influence of computer-self efficacy on motivation to use e-learning systems by Library and Information Science (LIS) undergraduates of Ajayi Crowther University, Oyo and Lead City University, Ibadan, Oyo State Nigeria.
Sunday Tunmibi, Olawumi Grace Oyadele
doaj   +1 more source

Review of Componential Analysis of General Vocabulary: The Semantic Structure of a Set of Verbs in English, Hindi, and Japanese, Part II, Bendix, Edward Herman (I.J.A.L. Vol. 32, No. 2, Publication 41) 1966 [PDF]

open access: yes, 1968
Sponsored in part by the National Science Foundation through Grant GN 534.1 from the Office of Science Information Service to the Computer and Information Science Research Center, The Ohio State ...
Fillmore, Charles J.
core  

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

A new cross-platform architecture for epi-info software suite

open access: yesBMC Bioinformatics, 2018
Background The Epi-Info software suite, built and maintained by the Centers for Disease Control and Prevention (CDC), is widely used by epidemiologists and public health researchers to collect and analyze public health data, especially in the event of ...
Blake Camp   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Relative Clause Structures and Constraints on Types of Complex Sentences [PDF]

open access: yes, 1970
Sponsored in part by the National Science Foundation through Grant GN-534.1 from the Office of Science Information Service to the Computer and Information Science Research Center, The Ohio State ...
Thompson, Sandra Annear
core  

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