Results 131 to 140 of about 3,792,174 (367)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Modern trends in knowledge representation and expert system technology
Le Matematiche, 1988 We will not be concerned with hardware aspects but we will discuss the present state of methodological concepts and software tools. Our main examples stem from the research activities at the Computer Science Department of the University of Kaiserslautern.
Klaus Nökel, Michael M. Richter
doaj
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
IEEE AccessOver the last decade, Data Science has emerged as one of the most important subjects that has had a major impact on industry. This is due to the continual development of scientific methods, algorithms, processes, and computational tools that help to ...
Harry D. Mafukidze +5 more
doaj +1 more source
The methodology of multicriterial assessment of Petri nets’ apparatus
MATEC Web of Conferences, 2016 This article emphasizes the effectiveness and relevance of the using of the apparatus of Petri nets for modeling of complex computing systems. Due to the fact that the methods of analysis existing in this theory do not allow estimating the resources ...
Pashchenko Dmitry +6 more
doaj +1 more source
THE EFFECTS OF SOCIAL MEDIA ADDICTION AMONG STUDENTS IN THE TERTIARY INSTITUTION: A CASE STUDY OF THE DEPARTMENT OF COMPUTER SCIENCE, KOGI STATE UNIVERSITY, ANYIGBA, KOGI STATE, NIGERIA [PDF]
, 2022 Daniel Musa Alih +2 more
openalex +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
Revista Colombiana de Computación, 2001 Un cordial saludo de parte de la Revista Colombiana de Computación y de todos sus colaboradores, con los mejores deseos para el año 2002. Queremos compartir con ustedes las novedades que hemos tenido.
Álvaro Enrique Arenas +1 more
doaj
MATEC Web of Conferences, 2016 This article gives a brief analysis of the subject area and the approaches to the analysis and synthesis of models of complex systems structures were discussed.
Pashchenko Dmitry +5 more
doaj +1 more source