Results 141 to 150 of about 3,141,228 (339)

A State-Wide Effort to Provide Access to Authentic Computer Science Education to Underrepresented Populations [PDF]

open access: gold, 2020
Mohammed A. Qazi   +4 more
openalex   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

About the problems of teaching future teacher-trainers in the condition of informatization of education

open access: yesRUDN Journal of Informatization in Education, 2014
In this article are considered actuality of informatization of professional education, about problems of readiness to use information and computer technology of professional activity of future teacher-trainers.
B K Mukhamedzhanov   +3 more
doaj  

We are entering a new era of problems: AI-generated images in research manuscripts

open access: yesOral Oncology Reports
This editorial highlights the significant threat of image fraud that may arise from the use of artificial intelligence (AI) generative technology in academic articles, which has been overlooked.
Kabir Suman Dash   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Extent of Utilization of Cloud Computing Resources by Students of Computer Science Education Department in Enugu State Universities, Nigeria [PDF]

open access: diamond, 2020
Eze Blessing Ngozi   +4 more
openalex   +1 more source

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