Results 71 to 80 of about 2,985,987 (318)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Text mining for social science – The state and the future of computational text analysis in sociology

open access: yesSocial Science Research, 2022
The emergence of big data and computational tools has introduced new possibilities for using large-scale textual sources in sociological research. Recent work in sociology of culture, science, and economic sociology has shown how computational text analysis can be used in theory building and testing.
openaire   +3 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Book Review: Guide to computer forensics and investigations (3rd ed.)

open access: yesJournal of Digital Forensics, Security and Law, 2008
Nelson, B., Phillips, A., Enfinger, F., & Steuart, C. (2008). Guide to computer forensics and investigations (3rd ed.). New Jersey: Pearson Education, Inc.
Keyu Jiang, Ruifeng Xuan
doaj  

Artificial intelligence: How is it changing medical sciences and its future?

open access: yesIndian Journal of Dermatology, 2020
Artificially intelligent computer systems are used extensively in medical sciences. Common applications include diagnosing patients, end-to-end drug discovery and development, improving communication between physician and patient, transcribing medical ...
Kanadpriya Basu   +3 more
doaj   +1 more source

Wright State University College of Engineering and Computer Science Bits and PCs newsletter, Volume 20, Number 7, May 2004 [PDF]

open access: yes, 2004
An eight page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.https://corescholar.libraries.wright.edu/bits_pcs/1137/thumbnail ...
Wright State University College of Engineering and Computer Science
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Computer Science in Transcaucasia and Baltic States: a Comparative Bibliometric Analysis

open access: yesMathematical Problems of Computer Science, 2019
Based on the Web of Science, InCites database, this article will analyze the publication output of the Transcaucasia and Baltic states in computer science research field, their citations, as well as international collaboration in the field of computer science. The obtained results demonstrate that publications on computer science from the Baltic states
Shushanik Sargsyan, Edita Gzoyan
openaire   +3 more sources

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Wright State University College of Engineering and Computer Science Bits and PCs newsletter, Volume 9, Number 3, March 1993 [PDF]

open access: yes, 1993
A twelve page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.https://corescholar.libraries.wright.edu/bits_pcs/1034/thumbnail ...
Wright State University College of Engineering and Computer Science
core   +2 more sources

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