Results 71 to 80 of about 391,544 (276)

Computer Science in Transcaucasia and Baltic States: a Comparative Bibliometric Analysis

Mathematical Problems of Computer Science, 2019
Based on the Web of Science, InCites database, this article will analyze the publication output of the Transcaucasia and Baltic states in computer science research field, their citations, as well as international collaboration in the field of computer science. The obtained results demonstrate that publications on computer science from the Baltic states
Shushanik Sargsyan, Edita Gzoyan
openaire   +3 more sources

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Computer Science Curriculum Redesign at Fort Valley State University [PDF]

2016 ASEE Annual Conference & Exposition Proceedings, 2016
The computer science program at Fort Valley State University (FVSU) , a unit of University System of Georgia, is presently undergoing a major revision to reflect the most current trends in the job market and the ABET computer science curriculum requirements.
Masoud Naghedolfeizi, Sanjeev Arora, Nabil A. Yousif, Xiangyan Zeng   +3 more
openaire   +2 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Cyberspace and Cybersecurity: Problems, Perspectives, Technologies

Цифрова платформа: інформаційні технології в соціокультурній сфері, 2018
The purpose of the article is to study and consider the general problems of such an important area of information activity of the state, business, education, science as cyber security.
Oleksandr Tkachenko, Kostiantyn Tkachenko   +1 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

The Importance of Free and Open Source Software and Open Standards in Modern Scientific Publishing

Publications, 2013
In this paper we outline the reasons why we believe a reliance on the use of proprietary computer software and proprietary file formats in scientific publication have negative implications for the conduct and reporting of science.
Vakhtang Tchantchaleishvili, Michael L. Wilson   +1 more
doaj   +1 more source

A State-Wide Effort to Provide Access to Authentic Computer Science Education to Underrepresented Populations [PDF]

, 2020
Mohammed A. Qazi, Jeff Gray, David Shannon, Melody Russell, Misty Thomas   +4 more
openalex   +1 more source