Results 81 to 90 of about 19,255,488 (244)

Other title: SRC annual report; Other title: State Rehabilitation Council annual report

open access: yes, 2012
Annual; Report year ends Sept. 30.; Issued by: State Rehabilitation Advisory Council, -2000/2001; by the State Rehabilitation Council, 2001 ...
Connecticut. State Rehabilitation Council.
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Other title: May Council meeting, progress report

open access: yes, 1958
"May 1958."MAY COUNCIL MEETING -- Status of Council Work -- Legislative Committee on Economy and Efficiency - Fourth Interim Report -- COUNCIL ACTION ON PROPOSALS -- Educational Survey - Pro. No. 7 -- Charges for Care in State Hospitals - Pro. No.
Kansas Legislature. Legislative Council.
core   +1 more source

Communiques on Activities of the State Environmental Council of Poland

open access: yesProblemy Ekorozwoju, 2009
The communication consist of: Letter from Council Chair Prof. Tomasz Winnicki to Polish Parliamentarians; The Standpoint of the State Environmental Council as Regards the Management of Solid Waste in Poland; The Standpoint of the State Environmental ...
Tomasz Winnicki
doaj  

School Council Member Perceptions and Actual Practice of School Councils in Rural Schools

open access: yesThe Rural Educator, 2018
In a time of growing interest in accountability, sharing school governance with parents, teachers, the community, and business leaders has become a norm. School councils or advisory groups have become a requirement for schools in many states.
Thomas Pharis   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Other title: May Council meeting : progress report

open access: yes, 1947
"May 1947."Kansas. Legislature. Legislative Council. -- Legislation--Kansas. -- Kansas--Politics and government. -- Y 7.4:MAY COUNCIL MEETING -- SUMMARY OF PROGRAM - PROPOSALS -- 1. Pollution of Fresh Water -- 2. Retirement of State and County Employees -
Kansas. Legislature. Legislative Council.
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Other title: September Council meeting : progress report

open access: yes, 1947
"September 1947."SEPTEMBER COUNCIL MEETING -- Status of Council Work -- New Proposals Introduced -- COMMITTEE ACTIVITY AND REPORTS -- Agriculture and Livestock -- Assessment and Taxation -- Proposal 5, Tax-Exempt Government Property -- Proposal 8 ...
Kansas Legislature. Legislative Council.
core   +1 more source

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