Results 61 to 70 of about 2,813,920 (263)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Secure state estimation against sensor attacks in the presence of noise [PDF]

open access: yes, 2017
We consider the problem of estimating the state of a noisy linear dynamical system when an unknown subset of sensors is arbitrarily corrupted by an adversary.
Diggavi, SN   +4 more
core   +1 more source

Distributed bounded-error state estimation for partitioned systems based on practical robust positive invariance

open access: yes, 2013
We propose a partition-based state estimator for linear discrete-time systems composed by coupled subsystems affected by bounded disturbances. The architecture is distributed in the sense that each subsystem is equipped with a local state estimator that ...
Ferrari-Trecate, G.   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Quantum state estimation using weak measurements

open access: yes, 2015
We explore the possibility of using "weak measurements" without "weak value" for quantum state estimation. Since for weak measurements the disturbance caused during each measurement is small, we can rescue the state, unlike for the case of projective ...
Arvind, Das, Debmalya
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Self-Organizing Distributed State Estimators [PDF]

open access: yes, 2012
Distributed solutions for signal processing techniques are important for establishing large-scale monitoring and control applications. They enable the deployment of scalable sensor networks for particular application areas. Typically, such networks consists of a large number of vulnerable components connected via unreliable communication links and are ...
Sijs, J., Papp, Z.
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Asymptotic quantum cloning is state estimation

open access: yes, 2006
The impossibility of perfect cloning and state estimation are two fundamental results in Quantum Mechanics. It has been conjectured that quantum cloning becomes equivalent to state estimation in the asymptotic regime where the number of clones tends to ...
Antonio Acín   +3 more
core   +1 more source

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