Results 81 to 90 of about 2,838,836 (274)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Sliding Mode Output Regulation for a Boost Power Converter

open access: yesEnergies, 2019
This work deals with the novel application of the sliding mode (discontinuous) output regulation theory to a nonlinear electrical circuit, the so-called boost power converter.
Jorge Rivera   +2 more
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Dynamic Sliding Mode Control of Spherical Bubble for Cavitation Suppression

open access: yesAxioms
Cavitation is a disadvantageous phenomenon that occurs when fluid pressure drops below its vapor pressure. Under these conditions, bubbles form in the fluid.
Ali Karami-Mollaee, Oscar Barambones
doaj   +1 more source

State feedback impulsive control of computer worm and virus with saturated incidence

open access: yesMathematical Biosciences and Engineering, 2018
A state feedback impulsive model is set up to discuss the spreading and control of the computer worm and virus. Considering the transmission features, saturated infectious is adopted to describe the spreading in the model, and all the treatment measures,
Meng Zhang   +3 more
doaj   +1 more source

Continuous quantum feedback of coherent oscillations in a solid-state qubit

open access: yes, 2005
We have analyzed theoretically the operation of the Bayesian quantum feedback of a solid-state qubit, designed to maintain perfect coherent oscillations in the qubit for arbitrarily long time.
A. N. Korotkov   +11 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Robust Control of Unknown Observable Nonlinear Systems Solved as a Zero-Sum Game

open access: yesIEEE Access, 2020
An optimal robust control solution for general nonlinear systems with unknown but observable dynamics is advanced here. The underlying Hamilton-Jacobi-Isaacs (HJI) equation of the corresponding zero-sum two-player game (ZS-TP-G) is learned using a Q ...
Mircea-Bogdan Radac, Timotei Lala
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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