Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Rare forms of nonalcoholic fatty liver disease: hereditary lysosomal acid lipase deficiency
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2016 Aim of review. To acquaint general practitioners with a rarely diagnosed disease - the hereditary deficiency of lysosomal acid lipase (DLAL) which can develop under the «mask» non-alcoholic fatty liver disease (NAFLD). Summary.
M. V. Mayevskaya +5 more
doaj +1 more source
Primary school mobile dental program in New South Wales, Australia: protocol for the evaluation of a state government oral health initiative. [PDF]
BMC Public Health, 2023 Balasubramanian M +16 more
europepmc +1 more source
Governability, governance…in short, the state
Revista Administración Pública y Sociedad, 2017 Governability is an old and significant worry and a part of the speech of political western thought. It appears under this concept when a systemic crisis of wellbeing capitalism casts some doubt on governments’ capacity and stability to make legitimate and effective decisions.
openaire +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
South Carolina State Library-services to South Carolina state government frequently asked questions [PDF]
, 2002 This handout lists frequently asked questions about State Library resources and services available to state ...
South Carolina State Library
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Mortality versus Municipal and State Government Spending in American Cities. [PDF]
J Urban Health, 2021 MacKenzie T, Lebeaux R.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Government to government annual report [PDF]
, 2005 This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Ceased with 2005Mode of access: Internet from the Oregon ...
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source