Results 91 to 100 of about 483,839 (260)
Local government debt report as of June 30, 2021
, 2021 The South Carolina Office of the State Treasurer annually publishes reports on the annual state debt and local government debt. The local debt report provides information on the outstanding debt obligations of all local governments, as submitted to the ...
South Carolina Office of the State Treasurer
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Sustainability of state government debts in Brazil [PDF]
EconomiAPurposeThis paper evaluates the sustainability of subnational government debts in Brazil, with a focus on how borrowing costs compared to revenue growth and how fiscal policy contributed to debt dynamics from 2007 to 2022.Design/methodology/approachThe ...
Felipe Soares Luduvice +1 more
doaj +1 more source
South Carolina State Library-services to South Carolina state government frequently asked questions [PDF]
, 2002 This handout lists frequently asked questions about State Library resources and services available to state ...
South Carolina State Library
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Governability, governance…in short, the state
Revista Administración Pública y Sociedad, 2017 Governability is an old and significant worry and a part of the speech of political western thought. It appears under this concept when a systemic crisis of wellbeing capitalism casts some doubt on governments’ capacity and stability to make legitimate and effective decisions.
openaire +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Welcome to SC Connects for State Government
, 2002 This handout from the State Library provides information on full text databases available for state ...
South Carolina State Library
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