Results 71 to 80 of about 1,051,927 (309)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Public hearing before the Assembly State Government Committee on ACR-53 (initiative and referendum): February 11, 1986 [PDF]

open access: yes, 1986
The file has been edited to remove copyrighted materials.
New Jersey. Legislature. General Assembly. State Government Committee
core  

Sustainability of state government debts in Brazil [PDF]

open access: yesEconomiA
PurposeThis paper evaluates the sustainability of subnational government debts in Brazil, with a focus on how borrowing costs compared to revenue growth and how fiscal policy contributed to debt dynamics from 2007 to 2022.Design/methodology/approachThe ...
Felipe Soares Luduvice   +1 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Les hommes qui voulaient être rois II. Sociologie des États privés

open access: yesCybergeo, 2012
With the advent of the Internet, the number of private States projects, also called micronations, witnessed a strong increase. Several analysts thought they were witnessing a movement calling for the refoundation of the very concept of State, of ...
Frédéric Lasserre
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Local Government Debt Report June 30, 2015 [PDF]

open access: yes, 2014
The South Carolina Office of the State Treasurer annually publishes reports on the annual state debt and local government debt. The local debt report provides information on the outstanding debt obligations of all local governments, as submitted to the ...
South Carolina Office of the State Treasurer
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Local Government Debt Report June 30, 2013 [PDF]

open access: yes, 2013
The South Carolina Office of the State Treasurer annually publishes reports on the annual state debt and local government debt. The local debt report provides information on the outstanding debt obligations of all local governments, as submitted to the ...
South Carolina Office of the State Treasurer
core  

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