Results 61 to 70 of about 4,959,587 (308)

Modernisation, managerialism and the culture wars: the reshaping of the local welfare state in England [PDF]

, 2004
The story of local government over the last few decades is often summarised in the assertion that there has been a move away from institutional authority embodied in the structures of councils towards more complex networks of local governance ...
Cochrane, Allan
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Diagnostics of chronic small intestinal obstruction in patient with ectopic pancreas in the Meckel's diverticulum (case report)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2016
Aim of the case report presentation. To draw attention of general practitioners to the rare case of intestinal obstruction - intussusception of Meckel's diverticulum in small intestinal lumen. Key points.
Zinaida A. Lemeshko, O. S. Shifrin, A. V. Korolev, T. L. Lemina, I. A. Sokolina, A. Ye. Leonovich, K. A. Lesko, A. S. Tertychny, V. T. Ivashkin   +8 more
doaj   +1 more source

E-government adoption in Qatar: An investigation of the citizens' perspective [PDF]

, 2009
Electronic government (e-government) initiatives are in their early stages in many developing countries and faced with various issues pertaining to their implementation, adoption and diffusion.
Al-Shafi, S, Irani, Z, Lee, H, Weerakkody, V   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

STRUGGLE AGAINST ORGANIZED CRIMINALITY AND CORRUPTION AS SAFETY CONDITION FOR NORT-CAUCASIAN FEDERAL DISTRICT

Модернизация, инновация, развитие, 2016
In order to address the problem of safety in the North Caucasian region, suppression of underground gangs’ subversive and terroristic activities have been continuously undertaken for quite a long time within the frames of the military force strategy ...
G. V. Startsev
doaj  

Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of publication. To present with clinical guidelines of the Russian gastroenterological association on Clostridium difficile-associated disease management to practical doctors. Summary. Clostridium difficile-associated disease develops at disorders of
V. T. Ivashkin, N. D. Yushchuk, I. V. Mayev, Tatyana L Lapina, Ye. A. Poluektova, O. S. Shifrin, A. S. Tertychny, A. S. Trukhmanov, A. A. Sheptulin, Ye. K. Baranskaya, O. S. Lyashenko, K. V. Ivashkin   +11 more
doaj   +1 more source

The state of state and local government finance [PDF]

This paper provides an overview of the state-local government sector, a review of the short-run impact of the 2007-09 recession on state and local governments, and a brief summary of key long-run challenges state and local governments will encounter in ...
Ronald C. Fisher
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The role of polymorphism (rs1800566) of NAD(F)H quinone oxidoreductase-1 in development of acute pancreatitis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of investigation. To estimate the role of genetic polymorphism (rs1800566) of NAD(F)H quinone oxidoreductase-1 in development of acute pancreatitis in the Russian population. Material and methods.
T. A. Samgina, Y. V. Kanishchev, S. N. Grigor’Yev, P. M. Nazarenko, A. V. Polonikov   +4 more
doaj   +1 more source