Results 171 to 180 of about 250,446 (261)

Disenrollment Rate For Dual-Eligible Beneficiaries During Medicaid Unwinding, 2023-24. [PDF]

Health Aff (Millwood)
Roberts ET, Ruggiero D, Patel S, Ayanian JZ, Beathard E, Kirch M, Kullgren JT, Switzer G, Tipirneni R.   +8 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Dynamic copay health plans, AI-enabled price transparency, and member experience. [PDF]

Health Aff Sch
Debbarma A, Dowd BE.
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Implementing public health emergency operations centres according to an international framework in Ethiopia, Nigeria, and Senegal: Best practices and achievements, 2021. [PDF]

PLOS Glob Public Health
Fekadu ST, Li J, Huang Y, Mankoula W, Eteng W, Abdullah A, Lokossou V, Menchion CW, Rosenfeld E, Li Z, Ma J, Zhao C, Jie Z, Gebrewahid AL, Conteh I, Abayneh A, Assefa Z, Habebe S, Aniaku E, Benyeogor EI, Oladejo J, Li AB, Bousso A, Sonko I, Dieng AB, Braka F, Gueye AS, Chikwe I.   +27 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

'A New Pace of Life': A Mixed-Methods Exploration of Retirement Plans, Preparations and Experiences in Middle-Aged and Older Autistic and Non-Autistic Adults. [PDF]

Autism
Kowalczyk Z, Fadzil AHA, Ward I, Happé F, Stewart GR.   +4 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The All-Payer Claims Database After the Gobeille Supreme Court Decision: Assessing the Impact on Fatal Opioid-Related Overdose Research. [PDF]

Health Serv Res
Cordes J, Bauer C, Bernson D, Larochelle MR, Li W, Cao J, Dammann O, Stopka TJ.   +7 more
europepmc   +1 more source