Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Mass incarceration as a climate justice issue. [PDF]
LeMasters K +8 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Unapproved regenerative medicine for spinal cord injury in Japan. [PDF]
Ukon Y +10 more
europepmc +1 more source
Oncology Organization and Oncologist Networks Under Medicare Advantage Plans.
Hu X +10 more
europepmc +1 more source
Inequalities in mammograms and cervical biopsies provision in the public and private sectors of the Brazilian healthcare system and the availability of gynecology and obstetrics specialists. [PDF]
Dias IWH +6 more
europepmc +1 more source
Planning and Implementing Social Media Communication in a Public Health Crisis: An Analytical Perspective. [PDF]
Balogun BA +4 more
europepmc +1 more source
Variation in time to payment in Medicaid managed care: evidence from national TAF data, 2022. [PDF]
Zhu JM +5 more
europepmc +1 more source
Utilizing artificial intelligence to optimize psychological trauma intervention in social assistances. [PDF]
Zhang Y, Xiong W, Gao Y.
europepmc +1 more source

