Results 121 to 130 of about 3,119,332 (305)
Strategic Analysis on the Public Power INfluence [PDF]
Competitors, clients, suppliers, potential competitors, substitute products. All represent competitive forces, considered as being representative for characterising the competition relationships in all industries.
Gheorghe CARSTEA, Razvan-Andrei CORBOS
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Myth and Reality: Impact of Fiscal Transfers on Regional Convergence
Theory, Methodology, Practice, 2010 The decision makers of the European Union have committed themselves a great number of times in the past decades to decreasing the economic and social differences between regions in the member states.
György Kocziszky
doaj
A New Approach to Takeover Law and Regulatory Competition [PDF]
The development of U.S. state takeover law in the past three decades has produced considerable and quite possibly excessive protection for incumbent managers from hostile takeovers.
Allen Ferrell, Lucian Arye Bebchuk
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
scIVNL-seq resolves in vivo single-cell RNA dynamics of immune cells during Salmonella infection
Nature CommunicationsThe immune response against pathogens involves multiple cell state transitions and complex gene expression changes. Here, we establish a single-cell in vivo new RNA labeling sequencing method (scIVNL-seq) and apply it to survey time-resolved RNA dynamics
Zhen Xiong +14 more
doaj +1 more source
Beyond the Conservative Nanny State: Policies to Promote Self-Sufficiency Among the Wealthy [PDF]
In his book, The Conservative Nanny State, economist Dean Baker debunks the myth that conservatives favor the market over government intervention. In fact, conservatives rely on a range of "nanny state" policies that ensure the rich get richer while ...
Dean Baker
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Nature CommunicationsIscB, as the putative ancestor of Cas9, possesses a compact size, making it suitable for in vivo delivery. OgeuIscB is the first IscB protein known to function in eukaryotic cells but requires a complex TAM (NWRRNA).
Fei Zhang +5 more
doaj +1 more source