Results 31 to 40 of about 206,166,983 (298)

CRISIS OF REPRESENTATIVE DEMOCRACY IN SPAIN

open access: yesИбероамериканские тетради, 2017
The article examines the crisis of representative democracy in Spain, which is characterized by the growth of the population’s critical attitudes towards politicians and political institutions and the decline of the latter’s influence.
Sergey Khenkin
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

LA REALITAT DE L’ESTAT AUTONÒMIC REFLECTIDA EN LES SENTÈNCIES DEL TRIBUNAL CONSTITUCIONAL 130/2013 I 135/2013, RELATIVES A LA LLEI GENERAL DE SUBVENCIONS [PDF]

open access: yesRevista d'Estudis Autonòmics i Federals, 2014
This article analyses two different judgements of the Spanish Constitutional Court (judgments 130/2013 and 135/2013 on the Act 38/2003 on public subsidies) with the objective to highlight how they reflect some of the key aspects of the functioning of the
Gerard Martín i Alonso
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Making Autonomies Matter: Sub-State Actor Accommodation in the Nordic Council and the Nordic Council of Ministers - An Analysis of the Institutional Framework for Accommodating the Faroe Islands, Greenland and Åland within ‘Norden’. EDAP 3/2014 [PDF]

open access: yes, 2014
Sovereign powers are not absolute but exercised in varying areas and to varying degrees by sub-state, state and supra-state entities. The upward dispersion of power to international organisations carries implications for the sub-state level, while ...
Stephan, Sarah
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Parlamento, partidos y Estado autonómico : sobre la conveniencia de suprimir el Senado = Parliament, parties and State of autonomies : on the convenience of suppressing the Senate

open access: yesRevista de Derecho Político, 2012
Existe en la doctrina un acuerdo generalizado sobre la existencia de un déficit en la participación de las CCAA en las decisiones estatales. La aceptación de dicha premisa es lo que en última instancia justificaría la conversión del Senado en una cámara ...
Eva Sáenz Royo
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Evaluation of autonomies in the severely brain injured: the Progression of Autonomies Scale [PDF]

open access: yes, 2013
The aim of this study was to validate the Progression of Autonomies Scale (PAS) for the evaluation of autonomies in severe acquired brain injury patients.
Mazzucchi, Anna   +5 more
core   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

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