Results 51 to 60 of about 206,166,983 (298)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Autonomy of Church and State
, 2015 The primary concern underlying both the Establishment Clause and the Free Exercise Clause is autonomy — of the state, of churches, and of individuals. Two conceptions of autonomy have vied for preeminence in the United States, one based upon the ideal of complete independence of church and state, having separation as its goal, and the other based upon
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Why the Spanish State of Autonomies could be the right Example for the Bolivian State [PDF]
The study’s aim is to analyze and investigate the characteristics of the regions demanding autonomy in Eastern Bolivia. Therefore the study takes a look at the Spanish political model, which could serve in a comparing and evaluating framework.
Vondenhoff, Valentino
core
A New Look at National-state Transformations in the South of the RSFSR: Book Review: Gunaev E. A. National Autonomies of the South of Russia in the Soviet Period: Territorial Structure and Management System (using the example of Kalmykia) / resp. ed. K. N. Maksimov. Elista: KalmSC RAS, 2022. 400 p. [PDF]
The review was devoted to the monograph by E. A. Gunaev (Kalmyk Scientific Center of the Russian Academy of Sciences) “National Autonomies of the South of Russia in the Soviet period: Territorial Structure and Management System (on the example of ...
10.22162/2500-1523-2024-1-165-172
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The siege of indigenous autonomies due to the extractive mining model in Mexico
Iztapalapa, 2018 The siege of indigenous autonomies due to the extractive mining model in Mexico. This article aims to present an overview of the impacts thas has the mine extractivism activities on the indigineous autonomies, that has been undergoing in Mexico, that has
Laura R. Valladares de la Cruz
doaj
La cooperación intergubernamental en el Estado autonómico: situación y perspectivas [PDF]
Revista d'Estudis Autonòmics i Federals, 2012 As proclaimed by the Spanish Constitutional Court at an early stage, the existence of cooperative relations is inherent to the State of Autonomies, yet cooperation among the various regional authorities has been scarce in Spain, both qualitatively and ...
José Gabriel Ruiz González
doaj
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source