Results 61 to 70 of about 206,166,983 (298)

SPAIN AS THE STATE OF AUTONOMIES. PRINCIPLES BEHIND THE TERRITORIAL ORGANIZATION BETWEEN 1978 AND 1983

Humanities and Social Sciences, 2020
This article examines the territorial configuration of Spain between 1978 and 1983. The article investigates whether the scope of autonomy granted to the regions inhabited by “the historical nationalities” fulfilled their need of being independent from ...
Joanna JAROSZYK
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

La (difícil) construcción de autonomías indígenes en el Estado plurinacional de Bolivia. Consideraciones generales y una aproximación al caso de la Autonomía Guaraní Charagua Iyambae [PDF]

Revista d'Estudis Autonòmics i Federals, 2015
Since the entry into force of the new Constitution (January 2009), Bolivia has experienced important political and institutional transformations, marked by the spotlight of indigenous peoples after decades of strong mobilizations.
Pere Morell i Torra
doaj  

Church Autonomy in the United States

, 2023
In this book chapter, I explore the idea of religious group autonomy by looking at how it has developed in American law. My perspective is that of an American lawyer and academic who has only modest familiarity with the European system. But even with that modest familiarity, it seems clear that America has developed a strikingly robust and fairly ...
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

LSTA fiscal year ... state program report overview

, 2004
Annual; Electronic coverage as of Jan. 24, 2003: 1999-; Description based on: 1999; title from title screen (viewed 1/24/2003).; As part of the Library Services and Technology Act (LSTA) annual report which the State Library submitted to the Institute of
State Library of Ohio
core  

Federalism and constitution: States’ participation in constitutional reform as a guarantee of the federalisation process. (A study of Spain’s unique model)

Perspectives on Federalism, 2018
The aim of involving state members in reforming federal constitutions is to guarantee them the autonomy that they have been constitutionally granted.
Alberdi María Reyes Pérez
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Globalization and the Fiscal Autonomy of the State [PDF]

, 2002
This paper investigates the fiscal consequences of various measures of policy liberalization designed to increase the global integration of developing countries. Its principal conclusions are that globalization has further accentuated the fiscal constraints facing states, and that there is a cumulative process of causation between liberal policies and ...
openaire   +3 more sources