Results 71 to 80 of about 655,217 (269)

Entropy profile of NCR 18650 cylindrical cell at various states of health

open access: yesHeliyon
Entropy measurement at various states of charge (SOC) is a potential non-destructive tool for characterizing lithium-ion batteries; however, traditional potentiometric methods are time-consuming. To address this, we developed a fast potentiometric method
Yerkin Serik   +3 more
doaj   +1 more source

Charge modulations in the superconducting state of the cuprates [PDF]

open access: yesPhysical Review B, 2002
Motivated by the recent scanning tunneling microscopy (STM) and neutron scattering experiments, we investigate various charge density wave orders coexisting with superconductivity in the cuprate superconductors. The explicit expressions of the local density of states and its Fourier component at the ordering wavevector for the weak charge modulations ...
openaire   +2 more sources

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

SOC-SOH Estimation and Balance Control Based on Event-Triggered Distributed Optimal Kalman Consensus Filter

open access: yesEnergies
The inconsistency in state-of-charge (SOC) for electric vehicle batteries will cause component damage and lifespan reduction of batteries. Meanwhile, the consistency in the state-of-health (SOH) also negatively influences the consensus of SOC.
Xiaohan Fang, Moran Xu, Yuan Fan
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Research on the Dynamic and Energetic Performances of an Electric SUV in Real Driving Conditions

open access: yesDesigns
Electric vehicles have a limited driving range compared to conventional vehicles. This paper aims to present a particular study of the performances of electric vehicles based on real driving conditions on a cycle carried out using the general conditions ...
Alexandru-Adrian Ancuta   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

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