Results 51 to 60 of about 691,640 (219)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

SOC-SOH Estimation and Balance Control Based on Event-Triggered Distributed Optimal Kalman Consensus Filter

open access: yesEnergies
The inconsistency in state-of-charge (SOC) for electric vehicle batteries will cause component damage and lifespan reduction of batteries. Meanwhile, the consistency in the state-of-health (SOH) also negatively influences the consensus of SOC.
Xiaohan Fang, Moran Xu, Yuan Fan
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Research on the Dynamic and Energetic Performances of an Electric SUV in Real Driving Conditions

open access: yesDesigns
Electric vehicles have a limited driving range compared to conventional vehicles. This paper aims to present a particular study of the performances of electric vehicles based on real driving conditions on a cycle carried out using the general conditions ...
Alexandru-Adrian Ancuta   +2 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Online State of Charge and State of Health Estimation for a Lithium-Ion Battery Based on a Data–Model Fusion Method

open access: yesEnergies, 2018
The accurate monitoring of state of charge (SOC) and state of health (SOH) is critical for the reliable management of lithium-ion battery (LIB) systems.
Zhongbao Wei   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

A Fast Online State of Health Estimation Method for Lithium-Ion Batteries Based on Incremental Capacity Analysis

open access: yesEnergies, 2019
Efficient and accurate state of health (SoH) estimation is an important challenge for safe and efficient management of batteries. This paper proposes a fast and efficient online estimation method for lithium-ion batteries based on incremental capacity ...
Shaofei Qu   +4 more
doaj   +1 more source

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