Results 31 to 40 of about 691,640 (219)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Sequential Monte Carlo Methods for Discharge Time Prognosis in Lithium-ion Batteries

International Journal of Prognostics and Health Management, 2012
This paper presents the implementation of a particle-filtering-based prognostic framework that allows estimating the state-of-charge (SOC) and predicting the discharge time of energy storage devices (more specifically lithium-ion batteries). The proposed
Jorge F. Silva, Marcos E. Orchard, Benjamín Olivares, Matías Cerda   +3 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Battery Management Systems in Electric and Hybrid Vehicles

Energies, 2011
The battery management system (BMS) is a critical component of electric and hybrid electric vehicles. The purpose of the BMS is to guarantee safe and reliable battery operation.
Michael Pecht, Kwok L. Tsui, Yinjiao Xing, Eden W. M. Ma   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Intelligent SOX Estimation for Automotive Battery Management Systems: State-of-the-Art Deep Learning Approaches, Open Issues, and Future Research Opportunities

Energies, 2022
Real-time battery SOX estimation including the state of charge (SOC), state of energy (SOE), and state of health (SOH) is the crucial evaluation indicator to assess the performance of automotive battery management systems (BMSs).
Molla Shahadat Hossain Lipu, Tahia F. Karim, Shaheer Ansari, Md. Sazal Miah, Md. Siddikur Rahman, Sheikh T. Meraj, Rajvikram Madurai Elavarasan, Raghavendra Rajan Vijayaraghavan   +7 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Novel Test Procedure for Assessing Lead–Acid Batteries for Partial-State-of-Charge Duty Using Internal Resistance Charge Acceptance Technique

Batteries
Battery energy storage systems (BESSs) are often used in partial-state-of-charge (PSOC) operation due to the desire for flexibility of charge and discharge. Lead–acid batteries are a good candidate to be used in battery energy storage due to their safety,
Max Parker, Richard McMahon
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

East Meets West: A Whole-Person Approach in Integrated Care

International Journal of Integrated Care
Introduction: Whole-person approach represents a fundamental tenet of integrated care globally. However, there remains a lack of consensus regarding its precise definition and an inclination towards superficial and formal implementation.
Minmin Luo, Kexing Liu, Shanshan Hong
doaj   +1 more source