Results 41 to 50 of about 655,217 (269)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A low-cost amperometric sensor for the combined state-of-charge, capacity, and state-of-health monitoring of redox flow battery electrolytes

Energy Conversion and Management: X, 2022
We recently introduced an amperometric, temperature-independent, and calibration-free method for the measurement of the state-of-charge (SOC) of redox flow battery (RFB) electrolytes.
Christian Stolze, Philip Rohland, Karina Zub, Oliver Nolte, Martin D. Hager, Ulrich S. Schubert   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Stealing Our Smarts: Indigenous knowledge in On-Line Learning

Seminar.net, 2005
Tell me what you know….Knowledge  and knowing can be a very tricky thing.  Reflect on what you are fairly certain that you know. Self-certainty in human knowledge is a function of metacognition primarily.
Alison A. Carr-Chellman
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Sequential Monte Carlo Methods for Discharge Time Prognosis in Lithium-ion Batteries

International Journal of Prognostics and Health Management, 2012
This paper presents the implementation of a particle-filtering-based prognostic framework that allows estimating the state-of-charge (SOC) and predicting the discharge time of energy storage devices (more specifically lithium-ion batteries). The proposed
Jorge F. Silva, Marcos E. Orchard, Benjamín Olivares, Matías Cerda   +3 more
doaj  

Intelligent SOX Estimation for Automotive Battery Management Systems: State-of-the-Art Deep Learning Approaches, Open Issues, and Future Research Opportunities

Energies, 2022
Real-time battery SOX estimation including the state of charge (SOC), state of energy (SOE), and state of health (SOH) is the crucial evaluation indicator to assess the performance of automotive battery management systems (BMSs).
Molla Shahadat Hossain Lipu, Tahia F. Karim, Shaheer Ansari, Md. Sazal Miah, Md. Siddikur Rahman, Sheikh T. Meraj, Rajvikram Madurai Elavarasan, Raghavendra Rajan Vijayaraghavan   +7 more
doaj   +1 more source

Equation of State of Charged Rod Dispersions

The Journal of Physical Chemistry B, 2023
We study the accuracy of the theory of Stroobants, Lekkerkerker and Odijk, called SLO theory (Macromolecules 19 (1986) 2232-2238), to describe the thermodynamic properties of an isotropic fluid of charged rods. By incorporation of the effective diameter of the rods according to SLO theory into scaled particle theory (SPT) we obtain an expression for ...
Tuinier, Remco, Kuhnhold, Anja
openaire   +5 more sources