Results 141 to 150 of about 3,090,729 (363)

The ALI Principles: A Farewell to Fault—But What Remedy for the Egregious Marital Misconduct of an Abusive Spouse? [PDF]

open access: yes, 2001
The fundamental premise of this commentary is that the ALl has erred in not including appropriate nonfinancial fault-based factors in the Principles for three major reasons: 1) other no-fault laws, including no-fault automobile insurance law, no-fault ...
Swisher, Peter Nash
core   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

A exceção é a regra: os centros de detenção para imigrantes na Itália

open access: yesREMHU: Revista Interdisciplinar da Mobilidade Humana
No início dos anos 1990, diante do aumento exponencial dos fluxos migratórios, a Itália proclama o Estado de emergência para lidar com o fenômeno, adotando leis cada vez mais restritivas de ingresso e permanência no país e edificando espaços de exceção ...
Fernanda Di Flora Garcia
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Necropolitics and Pandemic Premediation in The Fall’s Neo-Western State of Exception

open access: yesThe Comics Grid: Journal of Comics Scholarship
Jared Muralt’s ongoing comics series The Fall (2018–) depicts a post-apocalyptic world ravaged by a flu pandemic, in which the responses to and consequences of the fictional disease outbreak premediated the reality of the COVID-19 spread. While embedding
Anna Marta Marini, Michael Fuchs
doaj   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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