Results 61 to 70 of about 3,021,739 (277)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
On a New Notion of Partial Refinement
, 2013 Formal specification techniques allow expressing idealized specifications, which abstract from restrictions that may arise in implementations. However, partial implementations are universal in software development due to practical limitations.
Sekerinski, Emil, Zhang, Tian
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Initial State Interactions for $K^-$-Proton Radiative Capture
, 1994 The effects of the initial state interactions on the $K^--p$ radiative capture branching ratios are examined and found to be quite sizable. A general coupled-channel formalism for both strong and electromagnetic channels using a particle basis is ...
A.D. Martin +41 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A invasão de Masséna em 1810 e as linhas de Torres Vedras: uma paradoxaL confluência de objectivos?
Ler História, 2010 The campaign of 1810-1811 is revisited and the paradoxical confluence of the objectives of both parties considered as an explanation of its characteristics.
Fernando Dores Costa
doaj +1 more source
, 2023 Abstract It is common to suggest that certain threats generate emergency conditions that permit leaders to abjure deontic principles or to violate rights in the name of the common good. The idea that emergencies represent a kind of moral free-for-all has led some to argue that we should reject the concept in its entirety.
openaire +1 more source
Berry Phase and Ground State Symmetry in H x h Dynamical Jahn-Teller Systems
, 1999 Due to the ubiquitous presence of a Berry phase, in most cases of dynamical Jahn-Teller systems the symmetry of the vibronic ground state is the same as that of the original degenerate electronic state. As a single exception, the linear H x h icosahedral
Manini, Nicola, Rios, Paolo De Los
core +1 more source
Origin of the Canonical Ensemble: Thermalization with Decoherence [PDF]
, 2009 We solve the time-dependent Schrodinger equation for the combination of a spin system interacting with a spin bath environment. In particular, we focus on the time development of the reduced density matrix of the spin system.
Abragam A. +30 more
core +4 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source