How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Does the COVID-19 pandemic lead to an infra-state of exception: Turkey's responses and dismantling its medico-scientific policies. [PDF]
Karatas IB.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A invasão de Masséna em 1810 e as linhas de Torres Vedras: uma paradoxaL confluência de objectivos?
The campaign of 1810-1811 is revisited and the paradoxical confluence of the objectives of both parties considered as an explanation of its characteristics.
Fernando Dores Costa
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Exception Handling in CIMOSA: the Magneti Marelli application 23 June 1997 1
this paper is to present a real industrial experience done at Magneti Marelli Ricambi, a company of the Fiat group. The scenario of the application is the distribution system of the entire enterprise.
Exception Handling
core
The citizenship amendment act and the national register of citizens: An Assamese state of exception? [PDF]
In 2019, civil strife and political unrest stemmed from the government’s ratification of the ‘Citizenship Amendment Act’ (“The 2019 Act”) which afforded citizenship to a select few religious minorities in Bangladesh, Afghanistan, and Pakistan, who as per
Sengupta, Raghav
core
The State of Exception Between Schmitt and Agamben: On Topographies of Exceptionalism and the Constitutionality of COVID Quarantine Measures (with Examples from the Irish Context). [PDF]
MagShamhráin R.
europepmc +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Mathematical models:a state of exception [PDF]
Models live in a state of exception. Their versatility, the variety of their methods, the impossibility of their falsification and their epistemic authority allow mathematical models to escape, better than other cases of quantification, the lenses of ...
Saltelli, Andrea +6 more
core +1 more source

