Results 71 to 80 of about 592,824 (257)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Capturing the minds: The role of child deportation in maintaining Russian authority over Ukraine’s occupied territories

European Journal of International Security
Russia’s systematic deportation and transfer of Ukrainian children from occupied territories since 2014 is a central instrument of Russian governance.
Jade McGlynn, Anastasiia Romaniuk
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Dynamics of Extreme Violence during the Indonesian National Revolution in Subang, 1945-1949

Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan
This research aims to reconstruct the patterns and impacts of violence that occurred in the Subang region, particularly in the Pamanoekan and Tjiasem lands (P & T Lands), during the early period of the Indonesian War of Independence.
Aji Samsudin, Ibnu Sodiq
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

De l’exception-comme-règle au véritable état d’exception. Walter Benjamin, penseur contemporain de l’exception

Tr@jectoires
Walter Benjamin’s research led him to reflect on the state of exception, even if his uses of the concept remain little known. Beginning with Ursprung des deutschen Trauerspiels, in which he drew on classical theories of exception, Benjamin's position ...
Anna Migliorini
doaj   +1 more source

Confrontation Between Judicial Activism and State of Exception

Academicus International Scientific Journal, 2017
The judiciary has excelled in the international and national scene, reaching role of great importance, thus creating opposition to the legislative and executive powers. The center of gravity of the sovereign power of the state moves toward the judiciary,
Alexandre Pedro Moura D’Almeida
doaj   +1 more source

Exceptional Bound States in the Continuum

Physical Review Letters
Bound states in the continuum and exceptional points are unique singularities of non-Hermitian systems. In optical implementations, the former demonstrate strong enhancement of the electromagnetic field, while the latter exhibit high sensitivity to small perturbations. Hence, exceptional points are being actively investigated as next-generation optical
Adrià Canós Valero, Zoltan Sztranyovszky, Egor A. Muljarov, Andrey Bogdanov, Thomas Weiss   +4 more
openaire   +3 more sources