Results 61 to 70 of about 3,036,018 (296)

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Factors Regulating the Discharge Frequency in Optomotor Fibres Of Carcinus Maenas [PDF]

open access: yes, 1971
The influence of the excited state of the animal on various motor neurone discharges and accompanying muscle action potentials was studied in the eyestalk of the crab, Carcinus maenas.
Fiore, L., Wiersma, C. A. G.
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Is the United States 'Exceptional'?

open access: yesSSRN Electronic Journal
"Exceptionalism" as an awareness of the differences between the United States and Europe (and the rest of the world) and a sense of superiority became components of American nationalism and have affected the way that Americans perceive the world and their role in it.
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A invasão de Masséna em 1810 e as linhas de Torres Vedras: uma paradoxaL confluência de objectivos?

open access: yesLer História, 2010
The campaign of 1810-1811 is revisited and the paradoxical confluence of the objectives of both parties considered as an explanation of its characteristics.
Fernando Dores Costa
doaj   +1 more source

Origin of the Canonical Ensemble: Thermalization with Decoherence [PDF]

open access: yes, 2009
We solve the time-dependent Schrodinger equation for the combination of a spin system interacting with a spin bath environment. In particular, we focus on the time development of the reduced density matrix of the spin system.
Abragam A.   +30 more
core   +4 more sources

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